ArticleKorean journal of anesthesiology2016
Effects of intraoperative single bolus fentanyl administration and remifentanil infusion on postoperative nausea and vomiting.
Article in Korean journal of anesthesiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Effect of remimazolam for general anesthesia on postoperative nausea and vomiting : A systematic review and meta-analysis.Die Anaesthesiologie · 2024Pooled it
- Does a combined intravenous-volatile anesthesia offer advantages compared to an intravenous or volatile anesthesia alone: a systematic review and meta-analysis.BMC anesthesiology · 2021Pooled it
- Pharmacologic interventions for postoperative nausea and vomiting after thyroidectomy: A systematic review and network meta-analysis.PloS one · 2021Pooled it
- Trial
- Effects of epidural anesthesia on postoperative nausea and vomiting in laparoscopic gynecological surgery: a randomized controlled trial.Journal of anesthesia · 2018Trial
- Trial
- Comprehensive Analysis of Strong Opioid Side Effects in Palliative Care Using the SIDER Database.Journal of clinical medicine · 2025Article
- Predicting Post-surgery Discharge Time in Pediatric Patients Using Machine Learning.Translational medicine @ UniSa · 2024Article
- Utilization of Pre-Anesthetic Medications for Major Surgical Procedures at a Tertiary Care Center: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2020Article
- Article
- Effect of electroacupuncture on thermal pain threshold and expression of calcitonin-gene related peptide, substance P and γ-aminobutyric acid in the cervical dorsal root ganglion of rats with incisional neck pain.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2017Article
- Article
- Novel anesthetic technique for combined intracavitary and interstitial brachytherapy for cervix cancer in an outpatient setting.Journal of contemporary brachytherapy · 2017Article
- Postoperative nausea and vomiting after thyroidectomy: a comparison between dexmedetomidine and remifentanil as part of balanced anesthesia.Korean journal of anesthesiology · 2017Article
- Is postoperative nausea and vomiting still the big "little" problem?Korean journal of anesthesiology · 2016Article
- Comparison of topical oxybuprocaine and intravenous fentanyl in pediatric strabismus surgery.Saudi journal of anaesthesiaArticle
- Efficacy of ultrasound-guided bilateral pecto-intercostal fascial plane block as a pre-emptive analgesic adjunct in patients undergoing cardiac surgery: A randomized, double-blinded study.Journal of anaesthesiology, clinical pharmacologyArticle
- [Development of a multivariable predictive model for postoperative nausea and vomiting after cancer surgery in adults].Brazilian journal of anesthesiology (Elsevier)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the use of postoperative opioids is a well-known risk factor for postoperative nausea and vomiting (PONV), few studies have been performed on the effects of intraoperative opioids on PONV. We examined the effects of a single bolus administration of fentanyl during anesthesia induction and the intraoperative infusion of remifentanil on PONV.
methodsTwo hundred and fifty women, aged 20 to 65 years and scheduled for thyroidectomy, were allocated to a control group (Group C), a single bolus administration of fentanyl 2 µg/kg during anesthesia induction (Group F), or 2 ng/ ml of effect-site concentration-controlled intraoperative infusion of remifentanil (Group R) groups. Anesthesia was maintained with sevoflurane and 50% N2O. The incidence and severity of PONV and use of rescue antiemetics were recorded at 2, 6, and 24 h postoperatively.
resultsGroup F showed higher incidences of nausea (60/82, 73% vs. 38/77, 49%; P = 0.008), vomiting (40/82, 49% vs. 23/77 30%; P = 0.041) and the use of rescue antiemetics (47/82, 57% vs. 29/77, 38%; P = 0.044) compared with Group C at postoperative 24 h. However, there were no significant differences in the incidence of PONV between Groups C and R. The overall incidences of PONV for postoperative 24 h were 49%, 73%, and 59% in Groups C, F, and R, respectively (P = 0.008).
conclusionsA single bolus administration of fentanyl 2 µg/kg during anesthesia induction increases the incidence of PONV, but intraoperative remifentanil infusion with 2 ng/ml effect-site concentration did not affect the incidence of PONV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.