Evidence map›Paper›PMID 26885239›Full record

ReviewInternational journal of clinical and experimental medicine2015

The epidemiology and risk factors of inflammatory bowel disease.

Yulan Ye, Zhi Pang, Weichang Chen, Songwen Ju, Chunli Zhou

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05313620 (Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events), which is not on this map. Cited by 96 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05313620 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events

TypeinterventionalSponsorFundación de Investigación Biomédica - Hospital Universitario de La PrincesaRan2022 to 2025Enrolled30ConditionsUlcerative Colitis, ThromboembolismArmsTofacitinib, Infliximab Adalimumab y Golimumab
3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Diet and inflammatory bowel disease: The Asian Working Group guidelines.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Guideline
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
  12. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Frontiers in microbiology · 2025
    Article
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yulan YeDepartment of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou 215006, Jiangsu, China.
Zhi PangDepartment of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou 215006, Jiangsu, China.
Weichang ChenDepartment of Gastroenterology, The First Affiliated Hospital of College of Medicine, Soochow University Suzhou 215000, Jiangsu, China.
Songwen JuDepartment of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou 215006, Jiangsu, China.
Chunli ZhouDepartment of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou 215006, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aimed to summarize the epidemiology (incidence, prevalence and morality) and risk factors of inflammatory bowel disease (IBD). IBD is a chronic, relapsing, inflammatory disorder of the gastrointestinal tract and includes Crohn's Disease (CD) and ulcerative colitis (UC). IBD has increasing incidence and prevalence in most of countries and becomes a global emerging disease. A westernized lifestyle or habits and some environmental factors have been found to contribute to the pathogenesis of IBD. The relevant risk factors include Smoking, hygiene hypothesis, microorganisms, appendectomy, medication, nutrition, and stress have all been found to be associated with the modality of IBD, but results are inconsistent on this issue in available studies. Therefore, more studies are required to identify and understand the environmental determinants of IBD.

Indexed as

environmental factorsIncidenceinflammatory bowel diseasemoralityprevalence

Identifiers

PMID26885239
PMCPMC4730025

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.