Evidence map›Paper›PMID 26885224›Full record

ArticleInternational journal of clinical and experimental medicine2015

Extramedullary relapse in lumbar spine of patient with acute promyelocytic leukemia after remission for 16 years: a case report and literature review.

Zhengmei He, Shandong Tao, Yuan Deng, Yue Chen, Lixiao Song, Banghe Ding, Kankan Chen, Liang Yu, Chunling Wang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhengmei HeDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Shandong TaoDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Yuan DengDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Yue ChenDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Lixiao SongDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Banghe DingDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Kankan ChenDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Liang YuDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Chunling WangDepartment of Hematology, Huai'an First People's Hospital, Nanjing Medical University Huai'an 223300, China.
Huaian First People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute promyelocytic leukemia (APL) is a common myeloid leukemia. At the newly diagnosed stage, it can be fatal because of the serious complication-disseminated intravascular coagulation. With the advent and early application of all-trans retinoic acid, most APL patients can achieve a long-term survival, and only a minority of patients will develop extramedullary relapse after remission. The most common site of extramedullary relapse is central nervous system, while other sites are relatively rare. Here, we report a particularly rare APL patient who experienced extramedullary relapse with lumbar spine as the isolated site after a rather long time of remission for 16 years. At the time of relapse, the main clinical manifestations of the patient are obvious low back pain, weakness in lower limbs and limitation of activity. After treatment of local radiotherapy combined with ATRA and arsenic trioxide, the patient achieved and maintained a second complete remission by now.

Indexed as

Acute promyelocytic leukemiacase reportextramedullary relapselumbar spinereview

Identifiers

PMID26885224
PMCPMC4730010
OpenAlexW2290828837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.