Evidence map›Paper›PMID 26885159›Full record

ArticleInternational journal of clinical and experimental medicine2015

Tooth loss and risk of oral squamous cell carcinoma in Chinese Han population.

Chenqi Zuo, Yaqiao Zhu, Xiayong Wang, Xiantao Zeng, Cui Huang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The Photomodulation Activity of Metformin Against Oral Microbiome.Journal of lasers in medical sciences · 2019
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chenqi ZuoThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan UniversityWuhan 430079, China; The Affiliated Huizhou Stomatological Hospital of Medical College of Jinan University & Huizhou Stomatological HospitalHuizhou 516001, China.
Yaqiao ZhuThe Affiliated Huizhou Stomatological Hospital of Medical College of Jinan University & Huizhou Stomatological Hospital Huizhou 516001, China.
Xiayong WangThe Affiliated Huizhou Stomatological Hospital of Medical College of Jinan University & Huizhou Stomatological Hospital Huizhou 516001, China.
Xiantao ZengDepartment of Stomatology, Taihe Hospital, Hubei University of Medicine China.
Cui HuangThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University Wuhan 430079, China.
Hubei University of Medicine · CNJinan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAssociation between tooth loss and oral cancer risk was investigated primary studies and meta-analyses, however, the results remain inconsistent. This study is to test the association between tooth loss and oral squamous cell carcinoma (OSCC) in Chinese Han population.

methodsCase-control study including histologically confirmed OSCC cases and healthy controls individually matched to the cases for age, sex, and district of residence between May 1, 2010, and Match 31, 2014. Univariate and multiple logistic regression models were used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs) using the STATA 12.0 software.

resultsFinally included 150 OSCC patients and 167 healthy controls. Cases had a significantly higher mean (SD) number of lost teeth than controls (10.03±6.62 vs. 8.69±5.20; P = 0.045). The results of univariate analysis and adjustment for smoking and alcohol showed a non-significant association between tooth loss and OSCC. After adjustment for age at diagnosis, gender, smoking, alcohol use, body mass index, and history of diabetes mellitus, those in the upper tertiles of lost tooth were significantly more likely to have OSCC (OR = 3.64, 95% CI = 1.15-11.53, P = 0.03; P for trend = 0.11) than in the lower tertiles. The unadjusted and adjusted results of per teeth also revealed non-significant association.

conclusionsTooth loss may be not associated with risk of oral cancer in this case-control study. The relevant large-scale studies in Chinese are suggested to perform.

Indexed as

case-controls studyOral canceroral squamous cell carcinomatooth loss

Identifiers

PMID26885159
PMCPMC4724005
OpenAlexW2419503091

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.