ArticleInternational journal of clinical and experimental medicine2015
Association of transforming growth factor-β1 polymorphisms with the risk of diabetes mellitus.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Analysis of the frequency of single nucleotide polymorphisms in cytokine genes in patients with New Onset Diabetes After Transplant.Scientific reports · 2021Trial
- Molecular Epidemiology of TGF-β1 Gene Variants and Their Relationship With Adult Type 2 Diabetes Mellitus Patients Visiting Injibara Comprehensive Hospital in Northwest Ethiopia: A Case-Control Study.Health science reports · 2026Article
- Effect of ESWT on the microcirculation of the lower extremity in rats with diabetic vasculopathy: An experimental animal study.Turkish journal of physical medicine and rehabilitation · 2026Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between transforming growth factor-β1 (TGF-β1) polymorphisms with the risk of diabetes mellitus (DM) remains elusive. We aimed to evaluate the relationship between TGF-β1 polymorphisms and DM risk. We searched the association studies according to a predefined criteria using electronic databases. The strength of association between TGF-β1 codon 10/25 polymorphisms and the risk of DM was evaluated by odds ratio (OR) with the corresponding 95% confidence interval (CI). Six case-control studies were identified for the analysis of the association between TGF-β1 codon 10/25 polymorphism and the risk of DM. CC genotype at the codon 10 polymorphism was associated with the risk of type 2 DM (T2DM) (P = 0.026, OR = 1.397, 95% CI = 1.041-1.874). No marked association was observed between codon 25 polymorphism and the risk of DM. No evidence of marked publication bias was observed. CC genotype at the TGF-β1 codon 10 site may be an indicator for the risk of T2DM. However, further larger studies should be performed in the future.
Indexed as
Identifiers
26885158PMC4724004W2442736628What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.