Evidence map›Paper›PMID 26885099›Full record

ArticleInternational journal of clinical and experimental medicine2015

Risk factors associated with diabetic retinopathy onset and progression in diabetes patients: a Taiwanese cohort study.

Shih-Ting Tseng, Su-Tze Chou, Boon-Hua Low, Feng-Lin Su

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 5 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shih-Ting TsengDepartment of Food and Nutrition, Providence UniversityTaiwan 200, Sec. 7, Taiwan Boulevard, Shalu District, Taichung 43301, Taiwan (R.O.C.); Department of Endocrinology and Metabolism, Kuang Tien General HospitalNo. 117, Shatian Road, Shalu District, Taichung 433, Taiwan (R.O.C.).
Su-Tze ChouDepartment of Endocrinology and Metabolism, Kuang Tien General Hospital No. 117, Shatian Road, Shalu District, Taichung 433, Taiwan (R.O.C.).
Boon-Hua LowDepartment of Food and Nutrition, Providence University Taiwan 200, Sec. 7, Taiwan Boulevard, Shalu District, Taichung 43301, Taiwan (R.O.C.).
Feng-Lin SuDepartment of Food and Nutrition, Providence University Taiwan 200, Sec. 7, Taiwan Boulevard, Shalu District, Taichung 43301, Taiwan (R.O.C.).
Providence University · TWKuang Tien General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is a common complication of type 2 diabetes mellitus (T2DM) and the leading cause of adult blindness. This study aimed to clarify the risk factors associated with DR onset and progression in patients with T2DM in Taiwan. This retrospective analysis enrolled 743 T2DM patients, including 170 with DR and 573 without DR at baseline who were enrolled in the Diabetes Shared-Care Program. The average follow-up period was 2.9 years. Variables, including demographic characteristics, DM duration, anthropometric data and clinical laboratory results, were compared between patients with DR at baseline, those with new-onset DR, and patients without DR using a chi-squared test and one-way ANOVA. A multivariate Cox proportional hazards model was performed to identify risk factors associated with progression of preexisting DR or new-onset DR. During the follow-up period, 38 (22.4%) patients with preexisting DR experienced disease progression, and 91 (15.9%) patients had new-onset DR. Multivariate analysis revealed that the presence of neuropathy (HR: 3.96, 95% CI: 1.84, 8.53) and diastolic blood pressure (HR: 1.05, 95% CI: 1.02, 1.08) were associated with increased risk of DR progression (both P < 0.001). Factors associated with new-onset DR included neuropathy, systolic BP, cholesterol, and updated mean of HbA1c (all P ≤ 0.001). The risk factors associated with DR onset and progression in Taiwanese patients with T2DM are different. Neuropathy and blood pressure increased the risk of both DR onset and progression; however, the risk of DR onset was also increased with updated mean of HbA1c and cholesterol.

Indexed as

Complicationsdiabetes mellitusdiabetic retinopathyglycated hemoglobinrisk factor

Identifiers

PMID26885099
PMCPMC4723944
OpenAlexW2470284251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.