ArticleInternational journal of clinical and experimental medicine2015
Meta-analysis of the effect of postoperative radiotherapy on prognosis of prostatic cancer following radical prostatectomy.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA systematic evaluation was carried out over the effectiveness and safety of postoperative radiotherapy following radical prostatectomy.
methodThe randomized controlled trials that were concerned with postoperative radiotherapy for prostatic cancer and published before June 2014 were searched in PubMed, EMBASE, Cochrane Library, CBM, CNKI and VIP databases. Two researchers conducted quality evaluation and data extraction independently for all included literature. Rev Man 5.2 software was used for statistical analysis.
resultsFinally 5 randomized control trials involving 2290 cases were included. Meta-analysis showed that the approaches of radical prostatectomy with or without postoperative radiotherapy did not differ significantly in terms of overall survival (HR=1.09, 95% C1: 0.75-1.60, P=0.65). However, significant difference was found in biochemical progression-free survival (HR=0.54, 95% CI: 0.42-0.69, P < 0.001).
conclusionEvidences show that postoperative radiotherapy following radical prostatectomy can increase biochemical progression-free survival but not overall survival.
Indexed as
Identifiers
26884977PMC4723822What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.