Evidence map›Paper›PMID 26884870›Full record

ArticleInternational journal of clinical and experimental pathology2015

Differences in extension patterns between adenoid cystic carcinoma of the nasopharynx and nasopharyngeal carcinoma on MRI.

Jun Dong, Li Tian, Sheng Li, Yunxian Mo, Lizhi Liu, Rui Zhong

Open access · greenAbstract readComparative Study
In one paragraph

Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jun DongDepartment of VIP Patients, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.
Li TianDepartment of Medical Imaging and Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.
Sheng LiDepartment of Medical Imaging and Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.
Yunxian MoDepartment of Medical Imaging and Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.
Lizhi LiuDepartment of Medical Imaging and Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.
Rui ZhongDepartment of Medical Imaging and Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to map differences in extension patterns between adenoid cystic carcinoma (ACC) of the nasopharynxandnasopharyngeal carcinomaon magnetic resonance imaging (MRI) and provide more information for treatments.

methodsMRI examinations and clinical records were reviewed in 18 patients with ACC of the nasopharynx and 182 patients with nasopharyngeal carcinoma (NPC). All patients had biopsy to confirm diagnosis. Differences between NPC and ACC in terms of extension patterns were identified by the retrospective analysis of images from patients undergoing MRI.

resultsPatients with ACC of the nasopharynx obtained a higher rate of staging T4 (14.3% vs. 38.9%, P = 0.007) and paralyzed cranial nerves (6.0% vs. 38.9%, P < 0.001). Epstein-Barr (EB) virus infection was not correlated with ACC incidence. No significant difference was observed in invasion to skull base between ACC of the nasopharynx and NPC (53.3% vs. 66.7%, P = 0.277). Involvement of cranial nerve canal (32.4% vs. 55.6%, P = 0.049) and cavernous sinus (13.7% vs. 33.3%, P = 0.028) was more frequently detected by MRI on patients with ACC of the nasopharynx. Lymph node metastasis was infrequently diagnosed in patients with ACC of the nasopharynx.

conclusionAs seen on MRI images, ACC of the nasopharynx is characterized by a high incidence of perineural invasion, frequent and aggressive local infiltration, and infrequently, lymph node metastasis.

Indexed as

Magnetic Resonance ImagingAdolescentAdultAgedBiopsyCarcinomaCarcinoma, Adenoid CysticChildChinaDiagnosis, DifferentialDisease ProgressionFemaleHumansIncidenceLymphatic MetastasisMaleAdenoid cystic carcinomaextension patternsMRInasopharyngeal carcinomaparalyzed cranial nerve

Identifiers

PMID26884870
PMCPMC4730083
OpenAlexW2411503023

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.