Evidence map›Paper›PMID 26884578›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2016

Burden of Geriatric Events Among Older Adults Undergoing Major Cancer Surgery.

Hung-Jui Tan, Debra Saliba, Lorna Kwan, Alison A Moore, Mark S Litwin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  3. Trial
  4. Trial
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  6. Observational
  7. Postoperative delirium in patients with cancer: a narrative review of major risk factors.Sao Paulo medical journal = Revista paulista de medicina · 2026
    Review
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  9. Article
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  12. Ovarian cancer in the older patient: where are we now? What to do next?Therapeutic advances in medical oncology · 2023
    Review
  13. Article
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  16. Perioperative Pain Management Issues Unique to Older Adults Undergoing Surgery: A Narrative Review.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hung-Jui TanHung-Jui Tan, Debra Saliba, Lorna Kwan, Alison A. Moore, and Mark S. Litwin, University of California, Los Angeles; and Debra Saliba, Greater Los Angeles VA Geriatric Research Education and Clinical Centers, Los Angeles, CA. htan@mednet.ucla.edu.
Debra SalibaHung-Jui Tan, Debra Saliba, Lorna Kwan, Alison A. Moore, and Mark S. Litwin, University of California, Los Angeles; and Debra Saliba, Greater Los Angeles VA Geriatric Research Education and Clinical Centers, Los Angeles, CA.
Lorna KwanHung-Jui Tan, Debra Saliba, Lorna Kwan, Alison A. Moore, and Mark S. Litwin, University of California, Los Angeles; and Debra Saliba, Greater Los Angeles VA Geriatric Research Education and Clinical Centers, Los Angeles, CA.
Alison A MooreHung-Jui Tan, Debra Saliba, Lorna Kwan, Alison A. Moore, and Mark S. Litwin, University of California, Los Angeles; and Debra Saliba, Greater Los Angeles VA Geriatric Research Education and Clinical Centers, Los Angeles, CA.
Mark S LitwinHung-Jui Tan, Debra Saliba, Lorna Kwan, Alison A. Moore, and Mark S. Litwin, University of California, Los Angeles; and Debra Saliba, Greater Los Angeles VA Geriatric Research Education and Clinical Centers, Los Angeles, CA.
University of California, Los Angeles · US

Funding

The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Homero Erwin del Pino · 2002 to 2026
$19.7M
UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2006 to 2017
$9.8M
Health Effects of Alcohol and Comorbidity in Older AdultsK24AA015957 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOORE, ALISON AHERN · 2007 to 2017
$1.8M
NIAAA NIH HHS K24 AA015957NIAAA NIH HHS K24AA15957NIA NIH HHS P30 AG021684NIA NIH HHS P30AG021684NIA NIH HHS P30 AG028748NIA NIH HHS P30AG028748
6 · The paper itself

Abstract

purposeMost malignancies are diagnosed in older adults who are potentially susceptible to aging-related health conditions; however, the manifestation of geriatric syndromes during surgical cancer treatment is not well quantified. Accordingly, we sought to assess the prevalence and ramifications of geriatric events during major surgery for cancer. PATIENTS AND

methodsUsing Nationwide Inpatient Sample data from 2009 to 2011, we examined hospital admissions for major cancer surgery among elderly patients (ie, age ≥ 65 years) and a referent group age 55 to 64 years. From these observations, we identified geriatric events that included delirium, dehydration, falls and fractures, failure to thrive, and pressure ulcers. We then estimated the collective prevalence of these events according to age, comorbidity, and cancer site and further explored their relationship with other hospital-based outcomes.

resultsWithin a weighted sample of 939,150 patients, we identified at least one event in 9.2% of patients. Geriatric events were most common among patients age ≥ 75 years, with a Charlson comorbidity score ≥ 2, and who were undergoing surgery for cancer of the bladder, ovary, colon and/or rectum, pancreas, or stomach (P < .001). Adjusting for patient and hospital characteristics, those patients who experienced a geriatric event had a greater likelihood of concurrent complications (odds ratio [OR], 3.73; 95% CI, 3.55 to 3.92), prolonged hospitalization (OR, 5.47; 95% CI, 5.16 to 5.80), incurring high cost (OR, 4.97; 95% CI, 4.58 to 5.39), inpatient mortality (OR, 3.22; 95% CI, 2.94 to 3.53), and a discharge disposition other than home (OR, 3.64; 95% CI, 3.46 to 3.84).

conclusionMany older patients who receive cancer-directed surgery experience a geriatric event, particularly those who undergo major abdominal surgery. These events are linked to operative morbidity, prolonged hospitalization, and more expensive health care. As our population ages, efforts focused on addressing conditions and complications that are more common in older adults will be essential to delivering high-quality cancer care.

Indexed as

Cost of IllnessAccidental FallsAgedAge FactorsComorbidityDehydrationDeliriumFailure to ThriveFemaleFractures, BoneHumansMaleMiddle AgedNeoplasmsOdds RatioPostoperative Complications

Identifiers

PMID26884578
PMCPMC4872324
OpenAlexW2277027128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.