Evidence map›Paper›PMID 26884410›Full record

ArticleComparative medicine2016

Use of an Implantable Loop Recorder in a Chimpanzee (Pan troglodytes) to Monitor Cardiac Arrhythmias and Assess the Effects of Acupuncture and Laser Therapy.

Elizabeth R Magden, Meg M Sleeper, Stephanie J Buchl, Rebekah A Jones, Erica J Thiele, Gregory K Wilkerson

Open access · greenAbstract readCase Reports
PubMed Full text at PMC
In one paragraph

Article in Comparative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. The Effects of Oral Lavender Therapy on Wounding in Chimpanzees (Animals : an open access journal from MDPI · 2023
    Article
  7. The Application of Laser Acupuncture in Animal Experiments: A Narrative Review of Biological Aspects.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  8. Article
  9. Differences in Behavior Between Elderly and Nonelderly Captive Chimpanzees and the Effects of the Social Environment.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  10. Animal welfare (South Mimms, England) · 2018
    Article
  11. Article
  12. Spotlight on acupuncture in laboratory animal medicine.Veterinary medicine (Auckland, N.Z.) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elizabeth R MagdenMichale E Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, MD Anderson Cancer Center, Bastrop, Texas, USA. ermagden@mdanderson.org.
Meg M SleeperDepartment of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Stephanie J BuchlMichale E Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, MD Anderson Cancer Center, Bastrop, Texas, USA.
Rebekah A JonesMichale E Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, MD Anderson Cancer Center, Bastrop, Texas, USA.
Erica J ThieleMichale E Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, MD Anderson Cancer Center, Bastrop, Texas, USA.
Gregory K WilkersonMichale E Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, MD Anderson Cancer Center, Bastrop, Texas, USA.
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is a leading cause of death in captive chimpanzees and is often associated with myocardial fibrosis, which increases the risk of cardiac arrhythmias. In this case report, we present a 36-y-old male chimpanzee (Pan troglodytes) diagnosed with frequent ventricular premature complexes (VPC). We placed a subcutaneous implantable loop recorder for continual ECG monitoring to assess his arrhythmias without the confounding effects of anesthetics. During his initial treatment with the antiarrhythmia medication amiodarone, he developed thrombocytopenia, and the drug was discontinued. After reviewing other potential therapies for the treatment of cardiac arrhythmias, we elected to try acupuncture and laser therapy in view of the positive results and the lack of adverse side effects reported in humans. We used 2 well-known cardiac acupuncture sites on the wrist, PC6 (pericardium 6) and HT7 (heart 7), and evaluated the results of the therapy by using the ECG recordings from the implantable loop recorder. Although periodic increases in the animal's excitement level introduced confounding variables that caused some variation in the data, acupuncture and laser therapy appeared to decrease the mean number of VPC/min in this chimpanzee.

Indexed as

Pan troglodytesAcupuncture TherapyAnimalsApe DiseasesElectrocardiography, AmbulatoryEquipment DesignHeart RateLaser TherapyMalePredictive Value of TestsTime FactorsTreatment OutcomeVentricular Premature Complexes

Identifiers

PMID26884410
PMCPMC4752036
OpenAlexW2430218189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.