Evidence map›Paper›PMID 26883881›Full record

ReviewNutrition reviews2016

Role of maternal vitamins in programming health and chronic disease.

Emanuela Pannia, Clara E Cho, Ruslan Kubant, Diana Sánchez-Hernández, Pedro S P Huot, G Harvey Anderson

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Nutrition reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Effects of high-fat diets on fetal growth in rodents: a systematic review.Reproductive biology and endocrinology : RB&E · 2019
    Pooled it
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  10. [6Nutrients · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emanuela PanniaE. Pannia, C.E. Cho, R. Kubant, D. Sánchez-Hernández, P.S.P. Huot, and G.H. Anderson are with the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. G.H. Anderson is with the Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Clara E ChoE. Pannia, C.E. Cho, R. Kubant, D. Sánchez-Hernández, P.S.P. Huot, and G.H. Anderson are with the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. G.H. Anderson is with the Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Ruslan KubantE. Pannia, C.E. Cho, R. Kubant, D. Sánchez-Hernández, P.S.P. Huot, and G.H. Anderson are with the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. G.H. Anderson is with the Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Diana Sánchez-HernándezE. Pannia, C.E. Cho, R. Kubant, D. Sánchez-Hernández, P.S.P. Huot, and G.H. Anderson are with the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. G.H. Anderson is with the Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Pedro S P HuotE. Pannia, C.E. Cho, R. Kubant, D. Sánchez-Hernández, P.S.P. Huot, and G.H. Anderson are with the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. G.H. Anderson is with the Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
G Harvey AndersonE. Pannia, C.E. Cho, R. Kubant, D. Sánchez-Hernández, P.S.P. Huot, and G.H. Anderson are with the Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. G.H. Anderson is with the Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. harvey.anderson@utoronto.ca.
University of Toronto · CA

Funding

Canadian Institutes of Health Research MOP-93624
6 · The paper itself

Abstract

Vitamin consumption prior to and during pregnancy has increased as a result of proactive recommendations by health professionals, wide availability of vitamin supplements, and liberal food-fortification policies. Folic acid, alone or in combination with other B vitamins, is the most recommended vitamin consumed during pregnancy because deficiency of this vitamin leads to birth defects in the infant. Folic acid and other B vitamins are also integral components of biochemical processes that are essential to the development of regulatory systems that control the ability of the offspring to adapt to the external environment. Although few human studies have investigated the lasting effects of high vitamin intakes during pregnancy, animal models have shown that excess vitamin supplementation during gestation is associated with negative metabolic effects in both the mothers and their offspring. This research from animal models, combined with the recognition that epigenetic regulation of gene expression is plastic, provides evidence for further examination of these relationships in the later life of pregnant women and their children.

Indexed as

Chronic DiseaseDietary SupplementsFood, FortifiedMaternal Nutritional Physiological PhenomenaAnimalsEpigenesis, GeneticFemaleHumansPregnancyVitaminsVitaminsfolic acidmethyl vitaminspostpartum obesitypregnancyvitamins.

Identifiers

PMID26883881
PMCPMC4892288
OpenAlexW2273866904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.