ArticleBiological research for nursing2016
Comparison of Low Back Pain Recovery and Persistence: A Descriptive Study of Characteristics at Pain Onset.
Article in Biological research for nursing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01981382 (Characterizing Pain Sensitivity in Persistent Nonspecific Low Back Pain), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Characterizing Pain Sensitivity in Persistent Nonspecific Low Back Pain
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- The clinical course of acute, subacute and persistent low back pain: a systematic review and meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Pooled it
- Is educational attainment associated with the onset and outcomes of low back pain? a systematic review and meta-analysis.PloS one · 2024Pooled it
- The importance of inflammatory biomarkers in non-specific acute and chronic low back pain: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Pooled it
- Elevated Production of Nociceptive CC Chemokines and sE-Selectin in Patients With Low Back Pain and the Effects of Spinal Manipulation: A Nonrandomized Clinical Trial.The Clinical journal of pain · 2018Trial
- Trial
- Severe Neck and Low Back Pain Predicts Severe Pain 5 Years Later in Older Men: A Cohort Study.Journal of pain research · 2025Article
- Pain sensation and gut microbiota profiles in older adults with heart failure.Interdisciplinary nursing research · 2023Article
- Article
- A feasibility study on yoga's mechanism of action for chronic low back pain: psychological and neurophysiological changes, including global gene expression and DNA methylation, following a yoga intervention for chronic low back pain.Pilot and feasibility studies · 2022Article
- Sex-Related Pain Behavioral Differences following Unilateral NGF Injections in a Rat Model of Low Back Pain.Biology · 2022Article
- Neurophysiological and transcriptomic predictors of chronic low back pain: Study protocol for a longitudinal inception cohort study.Research in nursing & health · 2022Article
- Investigating key predictors of persistent low back pain: A focus on psychological stress.Applied nursing research : ANR · 2021Article
- Quantitative Sensory Testing Across Chronic Pain Conditions and Use in Special Populations.Frontiers in pain research (Lausanne, Switzerland) · 2021Review
- Contribution of COMT and BDNF Genotype and Expression to the Risk of Transition From Acute to Chronic Low Back Pain.The Clinical journal of pain · 2020Article
- Central Sensitivity Is Associated with Poor Recovery of Pain: Prediction, Cluster, and Decision Tree Analyses.Pain research & management · 2020Article
- From acute to persistent low back pain: a longitudinal investigation of somatosensory changes using quantitative sensory testing-an exploratory study.Pain reports · 2018Article
- Quantitative Sensory Testing and Current Perception Threshold Testing in Patients With Chronic Pain Following Lower Extremity Fracture.Biological research for nursing · 2018Article
- Biological determinants of health: Genes, microbes, and metabolism exemplars of nursing science.Nursing outlookArticle
- Effects of Physical Activity on Neurophysiological and Gene Expression Profiles in Chronic Back Pain: Study Protocol.Nursing researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPersistent low back pain is a significant problem worldwide. Early identification and treatment of individuals at high risk for persistent low back pain have been suggested as strategies to decrease the rate of disability associated with this condition. PURPOSE: To examine and compare demographic, pain-related, psychological, and somatosensory characteristics in a cohort of participants with acute low back pain who later went on to experience persistent low back pain or whose pain resolved within the first 6 weeks after initial onset.
methodsA descriptive study was conducted among men and women 18-50 years of age who had an acute episode of low back pain. Study questionnaires were administered to collect demographic information and measures of pain, coping, reactivity, mood, work history and satisfaction, and disability. A standardized protocol of quantitative sensory testing was performed on each participant at the painful area of their low back and at a remote site on their arm.
resultsThe sample consisted of 48 participants, of whom 19 went on to develop persistent low back pain and 29 resolved. Compared to the resolved group, the persistent low back pain group was significantly older and had a lower level of educational attainment, a higher body mass index, and higher mean "least" pain score on the Brief Pain Inventory-Short Form. Significantly higher thermal detection thresholds at the painful and remote sites as well as signs of central sensitivity differentiated the persistent pain group from the resolved group during the acute stage of low back pain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.