ArticleScientific reports2016
Fire blight disease reactome: RNA-seq transcriptional profile of apple host plant defense responses to Erwinia amylovora pathogen infection.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transcriptomic responses to biotic stresses in Malus x domestica: a meta-analysis study.Scientific reports · 2018Pooled it
- Virulence Regulation and Lifestyle Transitions: The Role of c-di-GMP and Two-Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales.Molecular plant pathology · 2026Review
- Integrating multi-omics and machine learning for disease resistance prediction in legumes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Bacterial Lipopeptides Are Effective against Pear Fire Blight.Microorganisms · 2024Article
- Full-length transcriptome and RNA-Seq analyses reveal the resistance mechanism of sesame in response to Corynespora cassiicola.BMC plant biology · 2024Article
- Genetic Analysis of Partially Resistant and Susceptible Chickpea Cultivars in Response toInternational journal of molecular sciences · 2024Article
- Susceptibility Evaluation to Fire Blight and Genome-Wide Associations within a Collection of Asturian Apple Accessions.Plants (Basel, Switzerland) · 2023Article
- Transcriptome analysis reveals differential transcription in tomato (Solanum lycopersicum) following inoculation with Ralstonia solanacearum.Scientific reports · 2022Article
- Comparative transcriptomic responses of European and Japanese larches to infection by Phytophthora ramorum.BMC plant biology · 2022Article
- Host-derived chimeric peptides clear the causative bacteria and augment host innate immunity during infection: A case study of HLB in citrus and fire blight in apple.Frontiers in plant science · 2022Article
- Identification of Oil Palm's Consistently Upregulated Genes during Early Infections ofPlants (Basel, Switzerland) · 2021Article
- Transcriptional profile of AvrRpt2Scientific reports · 2021Article
- Multi-Omics Analysis Reveals the Dynamic Changes of RNA NFrontiers in microbiology · 2021Article
- Host-Pathogen Interactions betweenMicroorganisms · 2020Article
- Exploring sunflower responses to Sclerotinia head rot at early stages of infection using RNA-seq analysis.Scientific reports · 2020Article
- Transcriptional analyses of differential cultivars during resistant and susceptible interactions with Peronospora effusa, the causal agent of spinach downy mildew.Scientific reports · 2020Article
- Small RNA ArcZ Regulates Oxidative Stress Response Genes and Regulons inFrontiers in microbiology · 2019Article
- Review
- Differential gene regulatory pathways and co-expression networks associated with fire blight infection in apple (Horticulture research · 2019Article
- Fire blight host-pathogen interaction: proteome profiles of Erwinia amylovora infecting apple rootstocks.Scientific reports · 2018Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The molecular basis of resistance and susceptibility of host plants to fire blight, a major disease threat to pome fruit production globally, is largely unknown. RNA-sequencing data from challenged and mock-inoculated flowers were analyzed to assess the susceptible response of apple to the fire blight pathogen Erwinia amylovora. In presence of the pathogen 1,080 transcripts were differentially expressed at 48 h post inoculation. These included putative disease resistance, stress, pathogen related, general metabolic, and phytohormone related genes. Reads, mapped to regions on the apple genome where no genes were assigned, were used to identify potential novel genes and open reading frames. To identify transcripts specifically expressed in response to E. amylovora, RT-PCRs were conducted and compared to the expression patterns of the fire blight biocontrol agent Pantoea vagans strain C9-1, another apple pathogen Pseudomonas syringae pv. papulans, and mock inoculated apple flowers. This led to the identification of a peroxidase superfamily gene that was lower expressed in response to E. amylovora suggesting a potential role in the susceptibility response. Overall, this study provides the first transcriptional profile by RNA-seq of the host plant during fire blight disease and insights into the response of susceptible apple plants to E. amylovora.
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