Evidence map›Paper›PMID 26883368›Full record

Observational studyJournal of cardiovascular translational research2016

Clinical Outcome of Patients with Aortic Stenosis and Coronary Artery Disease Not Treated According to Current Recommendations.

Giuseppe Di Gioia, Mariano Pellicano, Gabor G Toth, Filip Casselman, Julien Adjedj, Frank Van Praet, Bernard Stockman, Ivan Degrieck, Bruno Trimarco, William Wijns and 2 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of cardiovascular translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giuseppe Di GioiaCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Mariano PellicanoCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Gabor G TothCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Filip CasselmanCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Julien AdjedjCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Frank Van PraetCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Bernard StockmanCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Ivan DegrieckCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Bruno TrimarcoDivision of Cardiology, Department of Advanced Biomedical Science, University of Naples Federico II, Naples, Italy.
William WijnsCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Bernard De BruyneCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium.
Emanuele BarbatoCardiovascular Research Center Aalst, OLV Hospital, Moorselbaan n. 164, B-9300, Aalst, Belgium. emanuele.barbato@olvz-aalst.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the clinical outcome of patients with moderate/severe aortic stenosis and significant coronary disease not treated according to guidelines, recommending combined aortic valve replacement (AVR) and coronary artery bypass grafting (CABG). From 2002 to 2010, we assessed death up to 5 years in 650 patients with moderate/severe aortic stenosis and at least one coronary lesion (>50 %): 23 % were treated conservatively (MT), 17 % with percutaneous coronary intervention (PCI), 11 % with AVR, and 49 % with combined CABG and AVR. At a median follow-up of 58 months, overall death decreased over the groups (MT, 68 % vs. PCI, 44 % vs. AVR, 34 % vs. CABG and AVR, 23 %, p < 0.01). Compared to the MT group, Cox regression analysis adjusted for potential confounders showed significantly reduced mortality in the PCI, AVR, and CABG and AVR groups. When combined CABG and AVR is not feasible, PCI or AVR alone still improves significantly long-term survival as compared with MT alone.

Indexed as

AgedAged, 80 and overAortic Valve StenosisCardiovascular AgentsChi-Square DistributionCoronary Artery BypassCoronary Artery DiseaseDelivery of Health CareFemaleGuideline AdherenceHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateMalePercutaneous Coronary InterventionPractice Guidelines as TopicCardiovascular AgentsAortic valve diseaseCoronary artery diseaseCoronary bypass graftsPercutaneous coronary intervention

Identifiers

PMID26883368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.