ArticlePlant cell reports2016
Magnaporthe oryzae effectors MoHEG13 and MoHEG16 interfere with host infection and MoHEG13 counteracts cell death caused by Magnaporthe-NLPs in tobacco.
Article in Plant cell reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Transcriptome Analysis Reveals Calcium-Induced Defense Response in Barley AgainstInternational journal of molecular sciences · 2026Article
- Pyricularia oryzae: Lab star and field scourge.Molecular plant pathology · 2024Review
- Recent Advances in Effector Research ofBiomolecules · 2023Review
- The transcriptional landscape of plant infection by the rice blast fungus Magnaporthe oryzae reveals distinct families of temporally co-regulated and structurally conserved effectors.The Plant cell · 2023Article
- The Devastating Rice Blast Airborne PathogenPathogens (Basel, Switzerland) · 2023Review
- Plant immune receptors interact with hemibiotrophic pathogens to activate plant immunity.Frontiers in microbiology · 2023Review
- Characterization of infected process and primary mechanism in rice Acuce defense against rice blast fungus, Magnaporthe oryzae.Plant molecular biology · 2022Article
- Advancement in the Breeding, Biotechnological and Genomic Tools towards Development of Durable Genetic Resistance against the Rice Blast Disease.Plants (Basel, Switzerland) · 2022Review
- ITRAQ-Based Proteomic Analysis of Wheat (Biology · 2022Article
- Gene deletion and constitutive expression of the pectate lyase gene 1 (MoPL1) lead to diminished virulence of Magnaporthe oryzae.Journal of microbiology (Seoul, Korea) · 2022Article
- Arms and ammunitions: effectors at the interface of rice and it's pathogens and pests.Rice (New York, N.Y.) · 2021Review
- Computational Structural Genomics Unravels Common Folds and Novel Families in the Secretome of Fungal PhytopathogenMolecular plant-microbe interactions : MPMI · 2021Article
- Type 2 Nep1-Like Proteins from the Biocontrol OomyceteJournal of fungi (Basel, Switzerland) · 2021Article
- Tandem DNA repeats contain cis-regulatory sequences that activate biotrophy-specific expression of Magnaporthe effector gene PWL2.Molecular plant pathology · 2021Article
- The Redox Proteome of Thiol Proteins in the Rice Blast FungusFrontiers in microbiology · 2021Article
- Screening of Secreted Proteins ofFrontiers in plant science · 2020Article
- Comparative secretome analysis of different smut fungi and identification of plant cell death-inducing secreted proteins from Tilletia horrida.BMC plant biology · 2019Article
- Functional Identification of Novel Cell Death-inducing Effector Proteins from Magnaporthe oryzae.Rice (New York, N.Y.) · 2019Article
- Rise of a Cereal Killer: The Biology of Magnaporthe oryzae Biotrophic Growth.Trends in microbiology · 2018Review
- Identification and characterization of suppressors of plant cell death (SPD) effectors from Magnaporthe oryzae.Molecular plant pathology · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageAdapted pathogens are able to modulate cell responses of their hosts most likely due to the activity of secreted effector molecules thereby enabling colonisation by ostensible nonhost pathogens. It is postulated that host and nonhost pathogens of a given plant species differ in their repertoire of secreted effector molecules that are able to suppress plant resistance. We pursued the strategy of identifying novel effectors of Magnaporthe oryzae, the causal agent of blast disease, by comparing the infection process of closely related host vs. nonhost Magnaporthe species on barley (Hordeum vulgare L.). When both types of pathogen simultaneously attacked the same cell, the nonhost isolate became a successful pathogen possibly due to potent effectors secreted by the host isolate. Microarray studies led to a set of M. oryzae Hypothetical Effector Genes (MoHEGs) which were classified as Early- and LateMoHEGs according to the maximal transcript abundance during colonization of barley. Interestingly, orthologs of these MoHEGs from a nonhost pathogen were similarly regulated when investigated in a host situation, suggesting evolutionary conserved functions. Knockout mutants of MoHEG16 from the group of EarlyMoHEGs were less virulent on barley and microscopic studies revealed an attenuated transition from epidermal to mesophyll colonization. MoHEG13, a LateMoHEG, was shown to antagonize cell death induced by M. oryzae Necrosis-and ethylene-inducing-protein-1 (Nep1)-like proteins in Nicotiana benthamiana. MoHEG13 has a virulence function as a knockout mutant showed attenuated disease progression when inoculated on barley.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.