Evidence map›Paper›PMID 26883144›Full record

ReviewHuman cell2016

Hematopoietic stem cells: multiparameter regulation.

Kedong Song, Liying Li, Yiwei Wang, Tianqing Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Frontiers in cell and developmental biology · 2021
    Article
  5. Review
  6. Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kedong SongState Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China. kedongsong@dlut.edu.cn.
Liying LiState Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China.
Yiwei WangBurns Research Group, ANZAC Research Institute, University of Sydney, Concord, NSW, 2139, Australia.
Tianqing LiuState Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian, 116024, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic stem cells (HSCs) are capable to self-renew with multi-potency which generated much excitement in clinical therapy. However, the main obstacle of HSCs in clinical application was insufficient number of HSCs which were derived from either bone marrow, peripheral blood or umbilical cord blood. This review briefly discusses the indispensable utility of growth factors and cytokines, stromal cells, extracellular matrix, bionic scaffold and microenvironment aiming to control the hematopoiesis in all directions and provide a better and comprehensive understanding for in vitro expansion of hematopoietic stem cells.

Indexed as

Cell DifferentiationHematopoietic Stem CellsBlood CellsBone Marrow CellsCytokinesExtracellular MatrixHematopoiesisHumansIntercellular Signaling Peptides and ProteinsStem Cell NicheStromal CellsCytokinesIntercellular Signaling Peptides and ProteinsEx vivo expansionHematopoietic stem cells (HSCs)Multiparameter regulation

Identifiers

PMID26883144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.