ArticleJAMA pediatrics2016
Fish Intake in Pregnancy and Child Growth: A Pooled Analysis of 15 European and US Birth Cohorts.
Article in JAMA pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- An Evaluation of Food and Nutrient Intake among Pregnant Women in The Netherlands: A Systematic Review.Nutrients · 2023Pooled it
- Breast milk n-3 long-chain polyunsaturated fatty acids and blood pressure: an individual participant meta-analysis.European journal of nutrition · 2021Pooled it
- Food Consumption, Nutrient Intake and Status during the First 1000 days of Life in the Netherlands: a Systematic Review.Nutrients · 2019Pooled it
- Global early-life cohorts for nutrition-neurodevelopment research including over 100 datasets representing over one million children.iScience · 2026Article
- Associations between maternal fish intakes, maternal and cord PUFA and longitudinal measures of child weight at birth, 20 months and at 7 and 13 years of age.The British journal of nutrition · 2026Article
- Association between Maternal Exposure to Per- and Polyfluoroalkyl Substances and Childhood Growth Trajectories up to 4 Years of Age: The Japan Environment and Children's Study.Environmental science & technology · 2025Article
- Drivers and barriers to fish and seafood consumption in the first 1000 days of life.NPJ science of food · 2025Article
- Optimal Intake of Animal-Source Foods: A Scoping Review to Inform a New WHO Guideline.Advances in nutrition (Bethesda, Md.) · 2025Article
- Prenatal per- and polyfluoroalkyl substance mixtures and weight for length from birth to 12 months: The New Hampshire Birth Cohort Study.The Science of the total environment · 2025Article
- Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants.Nature communications · 2025Article
- Associations between religious/spiritual beliefs and behaviours and dietary patterns: analysis of the parental generation in a prospective cohort study (ALSPAC) in Southwest England.Public health nutrition · 2023Article
- A focus group study of fish consumption behaviors among Asian women in Milwaukee, Wisconsin.Preventive medicine reports · 2023Article
- Effects of Agricultural Intensification on Mediterranean Diets: A Narrative Review.Foods (Basel, Switzerland) · 2023Review
- Protocol for a 20-year follow-up after a randomized controlled trial of a Mediterranean diet in pregnancy: maternal and offspring risk factors for cardiovascular disease.Frontiers in pediatrics · 2023Article
- REPRO_PL-Polish Mother and Child Cohort-Exposure, Health Status, and Neurobehavioral Assessments in Adolescents-Design and Cohort Update.International journal of environmental research and public health · 2022Article
- Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview.Environmental epidemiology (Philadelphia, Pa.) · 2021Review
- Maternal seafood intake during pregnancy, prenatal mercury exposure and child body mass index trajectories up to 8 years.International journal of epidemiology · 2021Article
- The EU Child Cohort Network's core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables.European journal of epidemiology · 2021Article
- The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents.European journal of epidemiology · 2020Article
- Estimated postnatal p,p'-DDT and p,p'-DDE levels and body mass index at 42 months of age in a longitudinal study of Japanese children.Environmental health : a global access science source · 2020Article
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Authors and funding
34 authors at 20 institutions in 12 countries.
Funding
Abstract
importanceMaternal fish intake in pregnancy has been shown to influence fetal growth. The extent to which fish intake affects childhood growth and obesity remains unclear.
objectiveTo examine whether fish intake in pregnancy is associated with offspring growth and the risk of childhood overweight and obesity. DESIGN, SETTING, AND
participantsMulticenter, population-based birth cohort study of singleton deliveries from 1996 to 2011 in Belgium, France, Greece, Ireland, Italy, the Netherlands, Norway, Poland, Portugal, Spain, and Massachusetts. A total of 26,184 pregnant women and their children were followed up at 2-year intervals until the age of 6 years. EXPOSURES: Consumption of fish during pregnancy. MAIN OUTCOMES AND MEASURES: We estimated offspring body mass index percentile trajectories from 3 months after birth to 6 years of age. We defined rapid infant growth as a weight gain z score greater than 0.67 from birth to 2 years and childhood overweight/obesity at 4 and 6 years as body mass index in the 85th percentile or higher for age and sex. We calculated cohort-specific effect estimates and combined them by random-effects meta-analysis.
resultsThis multicenter, population-based birth cohort study included the 26,184 pregnant women and their children. The median fish intake during pregnancy ranged from 0.5 times/week in Belgium to 4.45 times/week in Spain. Women who ate fish more than 3 times/week during pregnancy gave birth to offspring with higher body mass index values from infancy through middle childhood compared with women with lower fish intake (3 times/week or less). High fish intake during pregnancy (>3 times/week) was associated with increased risk of rapid infant growth, with an adjusted odds ratio (aOR) of 1.22 (95% CI, 1.05-1.42) and increased risk of offspring overweight/obesity at 4 years (aOR, 1.14 [95% CI, 0.99-1.32]) and 6 years (aOR, 1.22 [95% CI, 1.01-1.47]) compared with an intake of once per week or less. Interaction analysis showed that the effect of high fish intake during pregnancy on rapid infant growth was greater among girls (aOR, 1.31 [95% CI, 1.08-1.59]) than among boys (aOR, 1.11 [95% CI, 0.92-1.34]; P = .02 for interaction). CONCLUSIONS AND RELEVANCE: High maternal fish intake during pregnancy was associated with increased risk of rapid growth in infancy and childhood obesity. Our findings are in line with the fish intake limit proposed by the US Food and Drug Administration and Environmental Protection Agency.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.