Evidence map›Paper›PMID 26882469›Full record

SynthesisPloS one2016

Ambulatory Blood Pressure Monitoring in Individuals with HIV: A Systematic Review and Meta-Analysis.

Shia T Kent, Samantha G Bromfield, Greer A Burkholder, Louise Falzon, Suzanne Oparil, Edgar T Overton, Michael J Mugavero, Joseph E Schwartz, Daichi Shimbo, Paul Muntner

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania.Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
  10. Article
  11. Article
  12. Integrated care of hypertension and HIV infection.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Article
  13. Review
  14. [Undiagnosed arterial hypertension in HIV-infected patients on antiretroviral therapy].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2018
    Article
  15. Article
  16. Race and sex differences in ambulatory blood pressure measures among HIV+ adults.Journal of the American Society of Hypertension : JASH · 2017
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shia T KentDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Samantha G BromfieldDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Greer A BurkholderDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Louise FalzonCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.
Suzanne OparilDepartment of Medicine, Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Edgar T OvertonDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Michael J MugaveroDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Joseph E SchwartzCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.
Daichi ShimboCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
WORKSITE BLOOD PRESSURE STUDYP01HL047540 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI SLOAN, RICHARD P · 1993 to 2014
$27.7M
Depression, Biobehavioral Mechanisms, & CHD/Mortality OutcomesP01HL088117 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2008 to 2013
$12.5M
Midcareer Mentoring in Behavioral Cardiology: Depression & Cardiovascular DiseaseK24HL084034 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2006 to 2015
$1.6M
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
NHLBI NIH HHS K24 HL084034NHLBI NIH HHS K24HL084034NHLBI NIH HHS K24 HL125704NHLBI NIH HHS P01 HL047540NHLBI NIH HHS P01HL047540NHLBI NIH HHS P01 HL088117NHLBI NIH HHS P01HL088117NHLBI NIH HHS T32HL00745733NIAID NIH HHS P30 AI027767NIAID NIH HHS P30AI027767
6 · The paper itself

Abstract

introductionAbnormal diurnal blood pressure (BP) rhythms may contribute to the high cardiovascular disease risk in HIV-positive (HIV+) individuals. To synthesize the current literature on ambulatory BP monitoring (ABPM) in HIV+ individuals, a systematic literature review and meta-analysis were performed.

methodsMedical databases were searched through November 11, 2015 for studies that reported ABPM results in HIV+ individuals. Data were extracted by 2 reviewers and pooled differences between HIV+ and HIV-negative (HIV-) individuals in clinic BP and ABPM measures were calculated using random-effects inverse variance weighted models.

resultsOf 597 abstracts reviewed, 8 studies with HIV+ cohorts met the inclusion criteria. The 420 HIV+ and 714 HIV- individuals in 7 studies with HIV- comparison groups were pooled for analyses. The pooled absolute nocturnal systolic and diastolic BP declines were 3.16% (95% confidence interval [CI]: 1.13%, 5.20%) and 2.92% (95% CI: 1.64%, 4.19%) less, respectively, in HIV+ versus HIV- individuals. The pooled odds ratio for non-dipping systolic BP (nocturnal systolic BP decline <10%) in HIV+ versus HIV- individuals was 2.72 (95% CI: 1.92, 3.85). Differences in mean clinic, 24-hour, daytime, or nighttime BP were not statistically significant. I2 and heterogeneity chi-squared statistics indicated the presence of high heterogeneity for all outcomes except percent DBP dipping and non-dipping SBP pattern.

conclusionsAn abnormal diurnal BP pattern may be more common among HIV+ versus HIV- individuals. However, results were heterogeneous for most BP measures, suggesting more research in this area is needed.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryAntihypertensive AgentsAnti-Retroviral AgentsCircadian RhythmClinical Trials as TopicFemaleHIVHIV InfectionsHumansHypertensionMaleRisk FactorsAntihypertensive AgentsAnti-Retroviral Agents

Identifiers

PMID26882469
PMCPMC4755611

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.