Evidence map›Paper›PMID 26882460›Full record

ReviewCurrent opinion in HIV and AIDS2016

More than osteoporosis: age-specific issues in bone health.

Kristine M Erlandson, Giovanni Guaraldi, Julian Falutz

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in HIV and AIDS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bone Mineral Density Declines Twice as Quickly Among HIV-Infected Women Compared With Men.Journal of acquired immune deficiency syndromes (1999) · 2018
    Article
  7. Article
  8. Ageing and inflammation in patients with HIV infection.Clinical and experimental immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Kristine M ErlandsonaUniversity of Colorado, Aurora, Colorado, USA bUniversity of Modena and Reggio Emilia, Modena, Italy cMcGill University, Montreal, Quebec, Canada.
Giovanni Guaraldi
Julian Falutz
GTx (United States) · USMcGill University · CAUniversity of Modena and Reggio Emilia · IT

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DANIEL Holland BESSESEN · 1995 to 2026
$32.6M
The Impact of HIV and Aging on Physical Function and the Somatopause.K23AG050260 · NIA · UNIVERSITY OF COLORADO DENVER · PI ERLANDSON, KRISTINE MACE · 2014 to 2018
$946k
NIA NIH HHS K23 AG050260
6 · The paper itself

Abstract

purpose of reviewThe interaction between fall and fracture risk factors is an area of increasing clinical relevance, but little information is known about the age-specific issues in bone health unique to HIV-infected adults. The present review will focus on what is known about falls and fall risk factors among HIV-infected adults, and then review the association between decreased muscle, increased adiposity, and frailty with both low bone mineral density (BMD) and falls. RECENT

findingsThe rate of falls among middle-aged HIV-infected adults is similar to that of HIV-uninfected adults 65 years and older. Many of the clinical factors that contribute to low BMD overlap with risk factors for falls, resulting in a high risk of a serious fall among older adults with the greatest risk for a fracture. Low muscle mass, increased adiposity and metabolic syndrome, physical function impairment and frailty, common among older HIV-infected adults, contribute to an increased risk for low BMD and falls, and subsequently, may increase the risk of fracture among HIV-infected older adults. SUMMARY: Interventions with dual benefit on reducing fall risk and improving BMD are likely to have the greatest impact on fracture prevention in the older, HIV-infected adult.

Indexed as

Accidental FallsAdiposityOsteoporosisAgedAged, 80 and overFractures, BoneHIV InfectionsHumansMuscular AtrophyRisk Factors

Identifiers

PMID26882460
PMCPMC4859322
OpenAlexW2280925178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.