ArticleAIDS care2016
Factors associated with quality of life in middle-aged and older patients living with HIV.
Article in AIDS care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Behavioral and cognitive interventions to improve treatment adherence and access to HIV care among older adults in sub-Saharan Africa: an updated systematic review.Systematic reviews · 2018Pooled it
- Trial
- Study characteristics on health-related quality of life in older people living with human immunodeficiency virus: A narrative review.World journal of virology · 2025Article
- Perceived quality of life and associated lifestyle practices among older people living with HIV in Uganda. A cross-sectional study.Virusdisease · 2025Article
- Factors Associated with Adequate Quality of Life Levels in HIV Patients During a Five-Year Longitudinal Study.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025Observational
- The impact of geriatric syndromes on quality of life among older people living with HIV in Kampala, Uganda.Frontiers in public health · 2024Article
- Cluster-Based Multinomial Logistic Regression Model for Health-Related Quality of Life Among People Living with HIV in Brazil.AIDS and behavior · 2024Article
- Article
- Evaluation of the health-related quality of life and associated factors in Zimbabwean adults living with HIV: a cross-sectional study.BMC research notes · 2023Article
- Polypharmacy and health related quality of life among older adults on antiretroviral therapy in a tertiary hospital in Tanzania: a hospital-based cross-sectional study.BMC infectious diseases · 2023Article
- Factors associated with quality of life, depressive symptoms, and perceived stress among rural older adults living with HIV in the United States.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2023Article
- Driving habits, cognition, and health-related quality of life in middle-aged and older adults with HIV.Applied neuropsychology. Adult · 2023Article
- Psychological resilience is an independent correlate of health-related quality of life in middle-aged and older adults with HIV in the Deep South.Journal of health psychology · 2022Article
- The Role of Depressive Symptoms and Physical Activity Levels in Mediating the Association Between HIV Status and Neurocognitive Functions Among Individuals Aged at Least 50 Years in China: Cross-sectional Study.JMIR public health and surveillance · 2022Article
- Longitudinal trajectory of the association between quality of life and depression among people living with HIV in China: a mixed effects model.AIDS care · 2022Article
- Determinants of the quality of life amongst HIV clinic attendees in Malang, Indonesia.BMC public health · 2021Article
- Depression and quality of life in old age: a closer look.European journal of ageing · 2021Article
- Correlates of health-related quality of life among adults receiving combination antiretroviral therapy in coastal Kenya.Health and quality of life outcomes · 2020Article
- A supervised exercise intervention fails to improve depressive symptoms and quality of life among sedentary older adults with HIV infection.AIDS care · 2020Article
- HIV-related stigma, depression, and social support are associated with health-related quality of life among patients newly entering HIV care.AIDS care · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HIV infection has been historically considered a disease of young adults; however, adults aged 50 years and older represent now an increasing proportion of HIV cases worldwide, including in Portugal. In this context, given the considerable burden associated with living with HIV, the topic of quality-of-life (QoL) assessment has become increasingly relevant. The aims of this study were to examine the age-related differences in QoL and depressive symptoms of younger and middle-aged and older adults with HIV as well as the sociodemographic, HIV-related and depressive symptoms (cognitive-affective and somatic) associated with QoL domains. The sample consisted of 1194 HIV-infected patients, recruited from 10 Portuguese hospitals. QoL data were collected using the WHOQOL-HIV-Bref questionnaire. Patients also completed the Beck Depression Inventory. Of the 1194 patients, 185 (15.5%) were over 50 years old. Middle-aged and older patients reported significantly lower QoL in the physical, independence and social relationships domains. Regarding the specific facets of QoL, middle-aged and older patients reported significantly lower scores in seven of the 29 specific facets of the WHOQOL-HIV-Bref and higher scores in one facet (financial resources). Overall, among middle-aged and older patients, higher education, being employed, a shorter time since HIV diagnosis, use of combination anti-retroviral therapy and fewer depressive symptoms were significantly associated with higher QoL ratings. Our findings suggest that both cognitive-affective and somatic depressive symptoms account for significant variability in QoL scores in middle-aged and older patients. Because an important feature of healthy ageing is maintaining QoL, these data may provide useful information for tailoring age-appropriate and effective interventions to improve the mental health and QoL of middle-aged and older patients living with HIV.
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