ArticleACS nano2016
Stimuli-Responsive Programmed Specific Targeting in Nanomedicine.
Article in ACS nano, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed.
- Red Blood Cell-Derived Extracellular Vesicles for Gene and RNA Therapeutics: Biological, Engineering, and Translational Challenges.International journal of nanomedicine · 2026Review
- Engineering biopolymer nanoparticles for targeted nanomedicine in cancer therapy and food preservation.Frontiers in nutrition · 2026Review
- Molecular-Based Nanoplatform Leads to the Formation of a Self-Indicating Responsive Drug Delivery System.Molecules (Basel, Switzerland) · 2025Article
- Strategies, Challenges, and Prospects of Nanoparticles in Gynecological Malignancies.ACS omega · 2024Review
- Fluorinated macromolecular amphiphiles as prototypic molecular drones.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Therapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment.Cancers · 2023Review
- Thermoresponsive Block Copolymer Core-Shell Nanoparticles with Tunable Flow Behavior in Porous Media.ACS applied materials & interfaces · 2022Article
- Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization.Science advances · 2022Article
- Biopolymeric Prodrug Systems as Potential Antineoplastic Therapy.Pharmaceutics · 2022Review
- Improving Anticancer Activity of Chrysin using Tumor Microenvironment pH-Responsive and Self-Assembled Nanoparticles.ACS omega · 2022Article
- Intracellular KFrontiers in bioengineering and biotechnology · 2022Article
- Ultrasound-Responsive Smart Drug Delivery System of Lipid Coated Mesoporous Silica Nanoparticles.Pharmaceutics · 2021Article
- Insights into Multifunctional Nanoparticle-Based Drug Delivery Systems for Glioblastoma Treatment.Molecules (Basel, Switzerland) · 2021Review
- Stimuli-Responsive Iron Oxide Nanotheranostics: A Versatile and Powerful Approach for Cancer Therapy.Advanced healthcare materials · 2021Review
- Biomedical nanoparticle design: What we can learn from viruses.Journal of controlled release : official journal of the Controlled Release Society · 2021Review
- Improvement of Gold Nanorods in Photothermal Therapy: Recent Progress and Perspective.Frontiers in pharmacology · 2021Review
- Article
- Stimuli-Responsive Polymeric Nanoplatforms for Cancer Therapy.Frontiers in bioengineering and biotechnology · 2021Review
- Article
- Nano-MOFs as targeted drug delivery agents to combat antibiotic-resistant bacterial infections.Royal Society open science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Both passive targeting and actively enhanced cellular internalization play significant roles in tumor-targeted therapy. Programmed specific targeting, as a novel targeting strategy that exploits stimuli-responsive structures, expects that nanocarriers show high stability during blood circulation for efficient passive targeting, then respond to tumor internal or external stimuli and transform into more cell-interactive forms upon arrival at the tumor tissue for enhanced cellular internalization. In this Perspective, we introduce recent advances in the design and development of stimuli-responsive programmed specific targeting nanomedicines, which are based on switchable surface charge, activatable targeting molecules, and variable coatings, to combine the advantages of passive targeting and actively enhanced cellular internalization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.