Evidence map›Paper›PMID 26881102›Full record

ArticleNeural plasticity2016

Is the Frequency in Somatosensory Electrical Stimulation the Key Parameter in Modulating the Corticospinal Excitability of Healthy Volunteers and Stroke Patients with Spasticity?

Marco Antonio Cavalcanti Garcia, João Marcos Yamasaki Catunda, Marcio Nogueira de Souza, Ana Paula Fontana, Sandro Sperandei, Claudia D Vargas

Abstract read
In one paragraph

Article in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco Antonio Cavalcanti GarciaLaboratório de Instrumentação Biomédica, Programa de Engenharia Biomédica, COPPE, Universidade Federal do Rio de Janeiro, Avenida Horácio Macedo 2030, CT, Bloco H, Sala 327, Cidade Universitária, 21941-914 Ilha do Fundão, RJ, Brazil; Laboratório de Neurobiologia II, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho 373, CCS, Bloco G, Sala G1-019, Cidade Universitária, 21941-902 Ilha do Fundão, RJ, Brazil; Departamento de Biociências da Atividade Física, Escola de Educação Física e Desportos, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho 540, Cidade Universitária, 21941-599 Ilha do Fundão, RJ, Brazil.
João Marcos Yamasaki CatundaLaboratório de Instrumentação Biomédica, Programa de Engenharia Biomédica, COPPE, Universidade Federal do Rio de Janeiro, Avenida Horácio Macedo 2030, CT, Bloco H, Sala 327, Cidade Universitária, 21941-914 Ilha do Fundão, RJ, Brazil.
Marcio Nogueira de SouzaLaboratório de Instrumentação Biomédica, Programa de Engenharia Biomédica, COPPE, Universidade Federal do Rio de Janeiro, Avenida Horácio Macedo 2030, CT, Bloco H, Sala 327, Cidade Universitária, 21941-914 Ilha do Fundão, RJ, Brazil.
Ana Paula FontanaDepartamento de Fisioterapia, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho 373, CCS, Bloco K, Sala K2-49, Cidade Universitária, 21941-902 Ilha do Fundão, RJ, Brazil.
Sandro SperandeiInstituto de Comunicação e Informação Científica e Tecnológica em Saúde (ICICT), Fundação Oswaldo Cruz (FIOCRUZ), Avenida Brasil 4365, 21040-900 Manguinhos, RJ, Brazil.ORCID 0000-0001-5367-3397
Claudia D VargasLaboratório de Neurobiologia II, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho 373, CCS, Bloco G, Sala G1-019, Cidade Universitária, 21941-902 Ilha do Fundão, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatosensory electrical stimulation (SES) has been proposed as an approach to treat patients with sensory-motor impairment such as spasticity. However, there is still no consensus regarding which would be the adequate SES parameters to treat those deficits. Therefore, the aim of this study was to evaluate the effects of applying SES over the forearm muscles at four different frequencies of stimulation (3, 30, 150, and 300 Hz) and in two intervals of time (5' and 30') by means of transcranial magnetic stimulation and Hoffmann's reflex (H-reflex) in healthy volunteers (Experiments  I and II). A group of stroke patients (Experiment  III) was also preliminary evaluated to ascertain SES effects at a low frequency (3 Hz) applied for 30' over the forearm spastic flexors muscles by measuring the wrist joint passive torque. Motor evoked potentials and the H-reflex were collected from different forearm and hand muscles immediately before and after SES and up to 5' (Experiment  I) and 10' (Experiments  I and II) later. None of the investigated frequencies of SES was able to operate as a key in switching modulatory effects in the central nervous system of healthy volunteers and stroke patients with spasticity.

Indexed as

AdultElectric StimulationEvoked Potentials, MotorEvoked Potentials, SomatosensoryFemaleHealthy VolunteersH-ReflexHumansMaleMuscle SpasticityPilot ProjectsPyramidal TractsSomatosensory CortexStrokeYoung Adult

Identifiers

PMID26881102
PMCPMC4736758

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.