ReviewNeural plasticity2016
Obesity Reduces Cognitive and Motor Functions across the Lifespan.
Review in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of exercise interventions in hypoxic environment on cardiovascular function and maximal power output in obese or overweight individuals: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- ADHD is associated with migraine: a systematic review and meta-analysis.European child & adolescent psychiatry · 2018Pooled it
- Obesity-related differences in amygdala and hippocampal volume and metabolism before and after a placebo-controlled antidepressant trial in major depressive disorder.Scientific reports · 2026Trial
- Trial
- Trial
- Effects of Sleeve Gastrectomy on Cognitive Function, Metabolic Indexes and Related Hormones in Adolescents with Obesity.Obesity surgery · 2026Article
- Neural mechanisms linking Western diet consumption and cognitive impairment: a role for the vagus nerve.Clinical science (London, England : 1979) · 2026Review
- Obesity is linked to impaired sensorimotor synchronization during walking but not tapping.Scientific reports · 2026Article
- Addressing co-occurring chronic pain and obesity simultaneously in a behavioral intervention: a pilot trial.Pilot and feasibility studies · 2026Article
- Optimizing cognitive health and emotional well-being through daytime napping: current insights and future directions.Annals of medicine and surgery (2012) · 2026Review
- Effect of Laparoscopic Sleeve Gastrectomy on Female Sexual Function Index (FSFI) and Menstrual Function.Patient preference and adherence · 2026Article
- Neuroendocrine-immune perturbations in metabolic disease: pathophysiological mechanisms underlying cognitive impairment.Frontiers in human neuroscience · 2026Review
- A study on the impact of childhood obesity on health-related physical fitness through motor coordination-related functional pathways.Frontiers in nutrition · 2026Article
- The MIND diet, cognitive function, and well-being among healthy adults at midlife: a randomised feasibility trial.BMC nutrition · 2025Article
- Protective and Therapeutic Effects of Orlistat in Combination withMedicina (Kaunas, Lithuania) · 2025Article
- Differential effects of obesity and hypertension on brain structure and cognitive ability: A subgroup analysis from nested study.Journal of education and health promotion · 2025Article
- High-fat diet impairs the dendritic morphology of hippocampal CA1 pyramidal neurons in male but not female mice.Frontiers in nutrition · 2025Article
- Relationship between dietary intake and growth and development in Chinese pupils.Frontiers in public health · 2025Article
- Article
- Interactive Relations of Body Mass Index, Cardiorespiratory Fitness, and Sex to Cognitive Function in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and musculoskeletal system, respectively. Many factors, such as insulin/leptin dysregulation and inflammation, mediate the effect of obesity and cognition and motor behaviors. Substantial evidence has suggested exercise to be an effective way to improve obesity and related cognitive and motor dysfunctions. This paper aims to discuss the association of obesity with cognition and motor behaviors and its underlying mechanisms. Following this, mechanisms of exercise to improve obesity-related dysfunctions are described. Finally, implications and future research direction are raised.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.