Evidence map›Paper›PMID 26881090›Full record

ReviewNeural plasticity2016

Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity.

R Ramírez-Barrantes, C Cordova, H Poblete, P Muñoz, I Marchant, F Wianny, P Olivero

Open access · goldAbstract readReview
In one paragraph

Review in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. TRPV1 Channels in the Central Nervous System as Drug Targets.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. New Insights into TRP Ion Channels in Stem Cells.International journal of molecular sciences · 2022
    Review
  12. Optogenetic control of cancer cell survival in ChR2-transfected HeLa cells.International journal of experimental pathology · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Role of Oxidative Stress and CaFrontiers in cell and developmental biology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

R Ramírez-BarrantesEscuela de Medicina, Universidad de Valparaíso, Hontaneda 2664, 2341386 Valparaíso, Chile.
C CordovaEscuela de Medicina, Universidad de Valparaíso, Hontaneda 2664, 2341386 Valparaíso, Chile.
H PobleteInstitute of Computational Comparative Medicine, Nanotechnology Innovation Center of Kansas State, Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506-5802, USA.
P MuñozEscuela de Medicina, Universidad de Valparaíso, Hontaneda 2664, 2341386 Valparaíso, Chile.
I MarchantEscuela de Medicina, Universidad de Valparaíso, Hontaneda 2664, 2341386 Valparaíso, Chile.
F WiannyINSERM, U846, Stem Cell and Brain Research Institute, 18 Avenue Doyen Lépine, 69500 Bron, France; Université de Lyon, 69003 Lyon, France.
P OliveroEscuela de Medicina, Universidad de Valparaíso, Hontaneda 2664, 2341386 Valparaíso, Chile.
University of Valparaíso · CLInserm · FRKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of new strategies to renew and repair neuronal networks using neural plasticity induced by stem cell graft could enable new therapies to cure diseases that were considered lethal until now. In adequate microenvironment a neuronal progenitor must receive molecular signal of a specific cellular context to determine fate, differentiation, and location. TRPV1, a nonselective calcium channel, is expressed in neurogenic regions of the brain like the subgranular zone of the hippocampal dentate gyrus and the telencephalic subventricular zone, being valuable for neural differentiation and neural plasticity. Current data show that TRPV1 is involved in several neuronal functions as cytoskeleton dynamics, cell migration, survival, and regeneration of injured neurons, incorporating several stimuli in neurogenesis and network integration. The function of TRPV1 in the brain is under intensive investigation, due to multiple places where it has been detected and its sensitivity for different chemical and physical agonists, and a new role of TRPV1 in brain function is now emerging as a molecular tool for survival and control of neural stem cells.

Indexed as

AnimalsHumansNeural Stem CellsNeurogenesisNeuronal PlasticityProtein Structure, SecondaryProtein Structure, TertiaryTRPV Cation ChannelsTRPV1 protein, humanTRPV Cation Channels

Identifiers

PMID26881090
PMCPMC4736371
OpenAlexW2229449005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.