ReviewOxidative medicine and cellular longevity2016
Update on the Mechanisms of Pulmonary Inflammation and Oxidative Imbalance Induced by Exercise.
Review in Oxidative medicine and cellular longevity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- Impairment on Cardiopulmonary Function after Marathon: Role of Exhaled Nitric Oxide.Oxidative medicine and cellular longevity · 2019Trial
- HAntioxidants (Basel, Switzerland) · 2026Article
- Short-term high-intensity resistance training: a feasibility study on pulmonary, immune and physical-functional fitness benefits for older adults with metabolic syndrome.European journal of applied physiology · 2026Article
- Influence of a Standardized Lunging Exercise Test on BALF Cytology in Horses Suffering from Mild-Moderate Equine Asthma.Animals : an open access journal from MDPI · 2025Article
- Airway Inflammation Responses to Walking Roadside and Park Routes After School: A Real-World Crossover Study.European journal of sport science · 2025Article
- Equine Asthma Diagnostics: Review of Influencing Factors and Difficulties in Diagnosing Subclinical Disease.Animals : an open access journal from MDPI · 2024Review
- Investigating the relationship between asthma symptoms and severity with television watching, computer use, and internet access among 13-14-year-old children in Yazd, Iran.BMC pediatrics · 2024Article
- Endurance Exercise Training Alters Lipidomic Profiles of Plasma and Eight Tissues in Rats: a MoTrPAC study.Research square · 2024Article
- Review
- Oxidative Stress and Antioxidants in Chronic Rhinosinusitis with Nasal Polyps.Antioxidants (Basel, Switzerland) · 2023Review
- Review
- Effect of Silymarin Supplementation in Lung and Liver Histological Modifications during Exercise Training in a Rodent Model.Journal of functional morphology and kinesiology · 2021Article
- Changes in pulmonary and plasma oxidative stress and inflammation following eccentric and concentric cycling in stable COPD patients.European journal of applied physiology · 2021Article
- Airways to heaven: Caution needed when exercising during COVID-19.Medical hypotheses · 2021Article
- Acute FeNO and Blood Pressure Responses to Air Pollution Exposure in Young Adults during Physical Activity.International journal of environmental research and public health · 2020Article
- Humidity prevents the exercise-induced formation of hydrogen peroxide and nitrite in exhaled breath condensate in recreational cyclists.European journal of applied physiology · 2020Article
- Pulmonary and Respiratory Muscle Function in Response to Marathon and Ultra-Marathon Running: A Review.Sports medicine (Auckland, N.Z.) · 2019Review
- Effect of exercise duration on pro-oxidants and pH in exhaled breath condensate in humans.Journal of physiology and biochemistry · 2016Article
- The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma.Mediators of inflammation · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms involved in the generation of oxidative damage and lung inflammation induced by physical exercise are described. Changes in lung function induced by exercise involve cooling of the airways, fluid evaporation of the epithelial surface, increased contact with polluting substances, and activation of the local and systemic inflammatory response. The present work includes evidence obtained from the different types of exercise in terms of duration and intensity, the effect of both acute performance and chronic performance, and the influence of special conditions such as cold weather, high altitude, and polluted environments. Levels of prooxidants, antioxidants, oxidative damage to biomolecules, and cellularity, as well as levels of soluble mediators of the inflammatory response and its effects on tissues, are described in samples of lung origin. These samples include tissue homogenates, induced sputum, bronchoalveolar lavage fluid, biopsies, and exhaled breath condensate obtained in experimental protocols conducted on animal and human models. Finally, the need to simultaneously explore the oxidative/inflammatory parameters to establish the interrelation between them is highlighted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.