Evidence map›Paper›PMID 26880983›Full record

ReviewStem cells international2016

Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges.

Shukui Zhou, Kaile Zhang, Anthony Atala, Oula Khoury, Sean V Murphy, Weixin Zhao, Qiang Fu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cells international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Challenges of using tissue engineering methods in the treatment of hypospadias.Frontiers in bioengineering and biotechnology · 2025
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  11. AnFrontiers in endocrinology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Shukui ZhouDepartment of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Kaile ZhangDepartment of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Anthony AtalaWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USA.
Oula KhouryWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USA.
Sean V MurphyWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USA.
Weixin ZhaoWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USA.
Qiang FuDepartment of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Forest Institute · USShanghai Sixth People's Hospital · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autologous stem cells as well as many studies describing their applications for the treatment of SUI. In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy.

Identifiers

PMID26880983
PMCPMC4737006
OpenAlexW2233922722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.