Evidence map›Paper›PMID 26880960›Full record

ArticleStem cells international2016

Stem Cell Mobilization with G-CSF versus Cyclophosphamide plus G-CSF in Mexican Children.

José Eugenio Vázquez Meraz, José Arellano-Galindo, Armando Martínez Avalos, Emma Mendoza-García, Elva Jiménez-Hernández

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Stem cells international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

José Eugenio Vázquez MerazBanco de Sangre, Hospital General de Ecatepec las Américas, Simón Bolivar esq. Libertadores de América Fracc. las Américas, 55076 Ecatepec de Morelos, MEX, Mexico.
José Arellano-GalindoArea de Virología, Laboratorio de Microbiología y Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Mexico.
Armando Martínez AvalosDepartamento de Oncología, Instituto Nacional de Pediatría, Mexico.
Emma Mendoza-GarcíaLaboratorio de Hematología e Investigación, Hospital General de México, OD and Laboratorio Clínico, Central Hospital Infantil de México Federico Gómez, Ciudad de México, DF, Mexico.
Elva Jiménez-HernándezDepartamento de Hematología Pediátrica, UMAE CMN la Raza IMSS, Mexico.
Hospital General de México · MXHospital Infantil de México Federico Gómez · MXInstituto Nacional de Pediatria · MXMexican Social Security Institute · MXUniversidad de Ecatepec · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fifty-six aphaereses were performed in 23 pediatric patients with malignant hematological and solid tumors, following three different protocols for PBPC mobilization and distributed as follows: A: seventeen mobilized with 4 g/m(2) of cyclophosphamide (CFA) and 10 μg/kg/day of granulocyte colony stimulating factor (G-CSF), B: nineteen with CFA + G-CSF, and C: twenty only with G-CSF when the WBC count exceeded 10 × 10(9)/L. The average number of MNC/kg body weight (BW)/aphaeresis was 0.4 × 10(8) (0.1-1.4), 2.25 × 10(8) (0.56-6.28), and 1.02 × 10(8) (0.34-2.5) whereas the average number of CD34+ cells/kg BW/aphaeresis was 0.18 × 10(6)/kg (0.09-0.34), 1.04 × 10(6) (0.19-9.3), and 0.59 × 10(6) (0.17-0.87) and the count of CFU/kg BW/aphaeresis was 1.11 × 10(5) (0.31-2.12), 1.16 × 10(5) (0.64-2.97), and 1.12 × 10(5) (0.3-6.63) in groups A, B, and C, respectively. The collection was better in group B versus group A (p = 0.007 and p = 0.05, resp.) and in group C versus group A (p = 0.08 and p = 0.05, resp.). The collection of PBPCs was more effective in the group mobilized with CFM + G-CSF when the WBC exceeded 10 × 10(3)/μL in terms of MNC and CD34+ cells and there was no toxicity of the chemotherapy.

Identifiers

PMID26880960
PMCPMC4736431
OpenAlexW2227202821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.