ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2016
Infectious diseases of marine molluscs and host responses as revealed by genomic tools.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 146 citations in OpenAlex.
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- Morphological, ultrastructure and molecular characterization ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- Berberine, a Natural Compound That Demonstrates Antiviral Effects Against Ostreid Herpesvirus 1 Infection inViruses · 2025Article
- Development and validation of a 66K SNP array for the hard clam (Mercenaria mercenaria).BMC genomics · 2024Article
- High parasite prevalence in an ecosystem engineer correlated with both local- and landscape-level factors.Oecologia · 2024Article
- Expansion and diversity of caspases in Mytilus coruscus contribute to larval metamorphosis and environmental adaptation.BMC genomics · 2024Review
- Transcriptomic Response of the Atlantic Surfclam (Spisula solidissima) to Acute Heat Stress.Marine biotechnology (New York, N.Y.) · 2024Article
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- Assessment of Infection Prevalence and Intensity of Disease-Causing Parasitic ProtozoansMicroorganisms · 2023Article
- Development and Evaluation of High-Density SNP Arrays for the Eastern Oyster Crassostrea virginica.Marine biotechnology (New York, N.Y.) · 2023Article
- UnderstandingFrontiers in genetics · 2023Article
- RNA-Seq comparative study reveals molecular effectors linked to the resistance of Pinna nobilis to Haplosporidium pinnae parasite.Scientific reports · 2022Article
- Draft Genome Sequence of Pediococcus pentosaceus Strain PP16CC, Isolated from Oyster Crassostrea corteziensis.Microbiology resource announcements · 2022Article
- Spatial effects in parasite-induced marine diseases of immobile hosts.Royal Society open science · 2022Article
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- The expanded inhibitor of apoptosis gene family in oysters possesses novel domain architectures and may play diverse roles in apoptosis following immune challenge.BMC genomics · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More and more infectious diseases affect marine molluscs. Some diseases have impacted commercial species including MSX and Dermo of the eastern oyster, QPX of hard clams, withering syndrome of abalone and ostreid herpesvirus 1 (OsHV-1) infections of many molluscs. Although the exact transmission mechanisms are not well understood, human activities and associated environmental changes often correlate with increased disease prevalence. For instance, hatcheries and large-scale aquaculture create high host densities, which, along with increasing ocean temperature, might have contributed to OsHV-1 epizootics in scallops and oysters. A key to understanding linkages between the environment and disease is to understand how the environment affects the host immune system. Although we might be tempted to downplay the role of immunity in invertebrates, recent advances in genomics have provided insights into host and parasite genomes and revealed surprisingly sophisticated innate immune systems in molluscs. All major innate immune pathways are found in molluscs with many immune receptors, regulators and effectors expanded. The expanded gene families provide great diversity and complexity in innate immune response, which may be key to mollusc's defence against diverse pathogens in the absence of adaptive immunity. Further advances in host and parasite genomics should improve our understanding of genetic variation in parasite virulence and host disease resistance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.