Evidence map›Paper›PMID 26880623›Full record

ArticleeLife2016

NIH peer review percentile scores are poorly predictive of grant productivity.

Ferric C Fang, Anthony Bowen, Arturo Casadevall

Abstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. A framework for assessing the trustworthiness of scientific research findings.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  6. Alternative models of funding curiosity-driven research.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  8. The costs of competition in distributing scarce research funds.Proceedings of the National Academy of Sciences of the United States of America · 2024
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  10. Rethink funding by putting the lottery first.Nature human behaviour · 2023
    Article
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  12. Introduction to the special section "Reducing research waste in (health-related) quality of life research".Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ferric C FangDepartments of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle, United States.
Anthony BowenDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, United States.ORCID http://orcid.org/0000-0003-1064-8372
Arturo CasadevallDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
6 · The paper itself

Abstract

Peer review is widely used to assess grant applications so that the highest ranked applications can be funded. A number of studies have questioned the ability of peer review panels to predict the productivity of applications, but a recent analysis of grants funded by the National Institutes of Health (NIH) in the US found that the percentile scores awarded by peer review panels correlated with productivity as measured by citations of grant-supported publications. Here, based on a re-analysis of these data for the 102,740 funded grants with percentile scores of 20 or better, we report that these percentile scores are a poor discriminator of productivity. This underscores the limitations of peer review as a means of assessing grant applications in an era when typical success rates are often as low as about 10%.

Indexed as

Biomedical ResearchPeer Review, ResearchEfficiencyNational Institutes of Health (U.S.)United Statesgrantshuman biologymedicinenational institute of healthnonepeer reviewpolicyresearch funding

Identifiers

PMID26880623
PMCPMC4769156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.