ArticleeLife2016
Prediction of primary somatosensory neuron activity during active tactile exploration.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Variations in vibrissal geometry across the rat mystacial pad: base diameter, medulla, and taper.Journal of neurophysiology · 2017Pooled it
- An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Peri-head distance coding in the mouse brainstem.Neuron · 2026Article
- Whisker-based pre-neuronal and peripheral encoding of surface stickiness.bioRxiv : the preprint server for biology · 2026Article
- Club-like receptors respond to light touch but not to whisking.Nature communications · 2025Article
- Sensory adaptation in the barrel cortex during active sensation in the behaving mouse.Scientific reports · 2024Article
- Human tactile sensing and sensorimotor mechanism: from afferent tactile signals to efferent motor control.Nature communications · 2024Article
- Reliability and stability of tactile perception in the whisker somatosensory system.Frontiers in neuroscience · 2024Article
- Comparative morphology of the whiskers and faces of mice (Mus musculus) and rats (Rattus norvegicus).The Journal of experimental biology · 2023Article
- Pre-neuronal processing of haptic sensory cues via dispersive high-frequency vibrational modes.Scientific reports · 2023Article
- Facial neuromuscular junctions and brainstem nuclei are the target of tetanus neurotoxin in cephalic tetanus.JCI insight · 2023Article
- On the intrinsic curvature of animal whiskers.PloS one · 2023Article
- Demonstration of three-dimensional contact point determination and contour reconstruction during active whisking behavior of an awake rat.PLoS computational biology · 2022Article
- A novel stimulator to investigate the tuning of multi-whisker responsive neurons for speed and the direction of global motion: Contact-sensitive moving stimulator for multi-whisker stimulation.Journal of neuroscience methods · 2022Article
- STDP and the distribution of preferred phases in the whisker system.PLoS computational biology · 2021Article
- Continuous, multidimensional coding of 3D complex tactile stimuli by primary sensory neurons of the vibrissal system.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Of mice and monkeys: Somatosensory processing in two prominent animal models.Progress in neurobiology · 2021Review
- Gradient of tactile properties in the rat whisker pad.PLoS biology · 2020Article
- An elaborate sweep-stick code in rat barrel cortex.Science advances · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Primary sensory neurons form the interface between world and brain. Their function is well-understood during passive stimulation but, under natural behaving conditions, sense organs are under active, motor control. In an attempt to predict primary neuron firing under natural conditions of sensorimotor integration, we recorded from primary mechanosensory neurons of awake, head-fixed mice as they explored a pole with their whiskers, and simultaneously measured both whisker motion and forces with high-speed videography. Using Generalised Linear Models, we found that primary neuron responses were poorly predicted by whisker angle, but well-predicted by rotational forces acting on the whisker: both during touch and free-air whisker motion. These results are in apparent contrast to previous studies of passive stimulation, but could be reconciled by differences in the kinematics-force relationship between active and passive conditions. Thus, simple statistical models can predict rich neural activity elicited by natural, exploratory behaviour involving active movement of sense organs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.