ReviewHeart failure reviews2016
Heart failure and orthostatic hypotension.
Review in Heart failure reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05467735 (Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.
Who cites it
21 citing papers in PubMed, 48 citations in OpenAlex.
- Unveiling orthostatic hypotension in precapillary pulmonary hypertension.ERJ open research · 2026Article
- Delayed Cardiovascular Response to Acute Hypotension in Heart Failure Patients Compared to Healthy Adults.International journal of vascular medicine · 2026Article
- Prognostic Implications of Orthostatic Hypotension in Elective Coronary Artery Bypass Grafting.Medical science monitor : international medical journal of experimental and clinical research · 2025Observational
- Evaluation of Midodrine Utilization in Patients with Cancer and Heart Failure.Cardiovascular drugs and therapy · 2025Article
- Effect of Protein Supplementation on Orthostatic Hypotension in Older Adult Patients with Heart Failure.Geriatrics (Basel, Switzerland) · 2025Article
- Article
- Approaches for treating cardiovascular symptoms in Parkinson's disease.Therapeutic advances in neurological disorders · 2025Review
- Utricular dysfunction in patients with orthostatic hypotension.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Article
- Prognostic value of postural hypotension in hospitalized patients with heart failure.Scientific reports · 2022Article
- Association of orthostatic blood pressure response with incident heart failure: The Framingham Heart Study.PloS one · 2022Observational
- Social relationships and the risk of incident heart failure: results from a prospective population-based study of older men.European heart journal open · 2022Article
- Splanchnic nerve modulation in heart failure: mechanistic overview, initial clinical experience, and safety considerations.European journal of heart failure · 2021Review
- Differential diagnosis of orthostatic hypotension.Autonomic neuroscience : basic & clinical · 2020Review
- Compression therapy for leg oedema in patients with heart failure.ESC heart failure · 2020Review
- Addressing Orthostatic Hypotension in Heart Failure: Pathophysiology, Clinical Implications and Perspectives.Journal of cardiovascular translational research · 2020Review
- Target Doses of Heart Failure Medical Therapy and Blood Pressure: Insights From the CHAMP-HF Registry.JACC. Heart failure · 2019Observational
- Autonomic dysfunction is associated with cardiac remodelling in heart failure patients.ESC heart failure · 2018Article
- Orthostatic hypotension for the cardiologist.Current opinion in cardiology · 2018Review
- Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults.JAMA internal medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthostatic hypotension (OH) is traditionally defined as a fall of ≥20 mmHg in systolic and/or ≥10 mmHg in diastolic blood pressure within 3 min of active standing. OH is a common comorbidity among patients with heart failure (HF). A comprehensive review regarding the relationship between OH and HF has not been published in the English literature. Here we provide current information about concomitant HF and OH, including: pathophysiology, methods of evaluation, prevalence, risk factors, prognosis and management of OH in HF patients, as well as the incidence of HF among patients with OH. The prevalence of OH in HF ranges from 8 % among community-living individuals to 83 % in elderly hospitalized patients. Dizziness and palpitations are the most frequent OH symptoms. Main predisposing factors for OH are HF severity, non-ischemic HF etiology, prolonged bed rest, hypertension and polypharmacy. OH in HF is generally managed according to recommendations for treatment of OH in the non-HF population. However, since acceptable pharmacotherapy with fludrocortisone and midodrine is problematic in HF due to adverse effects, the management of OH is based mainly on non-pharmacologic interventions. Several prospective epidemiological studies reported that OH is independently associated with an increased risk of developing HF. Since OH is a common and frequently symptomatic condition in HF patients, its clinical implications should be emphasized. Longitudinal studies should be conducted to investigate the prognostic significance and optimal management of OH in the HF population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.