Evidence map›Paper›PMID 26880210›Full record

ArticleJournal of the American Chemical Society2016

Total Synthesis of (-)-Chromodorolide B.

Daniel J Tao, Yuriy Slutskyy, Larry E Overman

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Concise Synthesis of (-)-GAJournal of the American Chemical Society · 2023
    Article
  3. Review
  4. Article
  5. Forging C(spJournal of the American Chemical Society · 2019
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel J TaoDepartment of Chemistry, 1102 Natural Sciences II, University of California , Irvine, California 92697-2025, United States.
Yuriy SlutskyyDepartment of Chemistry, 1102 Natural Sciences II, University of California , Irvine, California 92697-2025, United States.
Larry E OvermanDepartment of Chemistry, 1102 Natural Sciences II, University of California , Irvine, California 92697-2025, United States.

Funding

New Methods for the Synthesis of Neurological Agents and Other Heterocyclic MolecR01GM098601 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI OVERMAN, LARRY E. · 2011 to 2014
$1.6M
Fragment-Coupling at Tertiary Carbons: Macrocarpal and Eucalyptin A DerivativesF31GM113494 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SLUTSKYY, YURIY · 2015 to 2017
$103k
NIGMS NIH HHS 1F31GM113494NIGMS NIH HHS F31 GM113494NIGMS NIH HHS R01 GM098601NIGMS NIH HHS R01GM098601
6 · The paper itself

Abstract

The first total synthesis of a chromodorolide diterpenoid is described. The synthesis features a bimolecular radical addition/cyclization/fragmentation cascade that unites butenolide and trans-hydrindane fragments while fashioning two C-C bonds and stereoselectively forming three of the ten contiguous stereocenters of chromodorolide B.

Indexed as

CyclizationDiterpenesMolecular Conformationchromodorolide BDiterpenes

Identifiers

PMID26880210
PMCPMC4864965

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.