Observational studyBMC infectious diseases2016
Sexually transmitted infections and use of contraceptives in women living with HIV in Denmark - the SHADE cohort.
Observational study in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Autoantibodies neutralizing type 1 interferons in two cohorts of people with HIV.Journal of human immunity · 2026Article
- Association between early sexual initiation and sexually transmitted infections among Peruvian reproductive-age women.Frontiers in public health · 2023Article
- Persistence of cervical high-risk human papillomavirus in women living with HIV in Denmark - the SHADE.BMC infectious diseases · 2019Observational
- Cardiac Microvascular Dysfunction in Women Living With HIV Is Associated With Cytomegalovirus Immunoglobulin G.Open forum infectious diseases · 2018Article
- Molecular diagnosis of genital tract infections among HIV-positive women in Iran.Iranian journal of microbiology · 2018Article
- The role of counseling on modern contraceptive utilization among HIV positive women: the case of Northwest Ethiopia.BMC women's health · 2018Article
- An Update on the Global Epidemiology of Syphilis.Current epidemiology reports · 2018Article
- Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark.BMC research notes · 2017Observational
- HIV disclosure and stigma among women living with HIV in Denmark.Journal of virus eradication · 2017Article
- Bacterial vaginosis, human papilloma virus and herpes viridae do not predict vaginal HIV RNA shedding in women living with HIV in Denmark.BMC infectious diseases · 2017Article
- Comparison of the Peripheral Reactive Hyperemia Index with Myocardial Perfusion Reserve byDiagnostics (Basel, Switzerland) · 2017Article
- Prevalence and distribution of cervical high-risk human papillomavirus and cytological abnormalities in women living with HIV in Denmark - the SHADE.BMC cancer · 2016Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo Danish guidelines for screening of sexually transmitted infections (STIs) in women living with HIV (WLWH) exist, except for annual syphilis testing. Drug-drug interaction between hormonal contraceptives and some types of highly active antiretroviral therapy (HAART) occurs. We assessed prevalence of STIs, contraceptive choices and predictors of condom use in a cohort of WLWH in Denmark.
methodsWLWH consecutively enrolled during their outpatient visits from 2011 to 2012. Gynaecological examination and an interview were performed at entry and 6-month follow-up. Inclusion criteria were HIV-1 infection and ≥ 18 years of age. Exclusion criteria were pregnancy, alcohol- or drug abuse impeding adherence to the protocol. At entry, participants were tested (and where appropriate, treated according to guidelines) for Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis, and herpes simplex (HSV-1 and HSV-2). At follow-up, predictors of condom use were estimated in sexually active WLWH.
resultsIn total, 334 of the 1,392 eligible WLWH in Denmark were included (median age and HIV duration: 42.5 and 11.3 years). Chlamydia trachomatis was present in four individuals (1 %), and six (2 %) tested positive for HSV-2 by PCR. None were positive for Neisseria gonorrhoeae, HSV-1 or had active syphilis. At follow-up, 252 (76 %) participated; 168 (70 %) were sexually active. Contraceptives were used by 124 (75 %); condoms were preferred (62 %). Having an HIV-negative partner predicted condom use (adjusted OR 3.89 (95 %CI 1.49-10.11)). In the group of participants of reproductive age without pregnancy desires 13 % used no birth-control. Possible drug-drug interaction between hormonal contraceptives and HAART was found in 13/14 WLWH receiving both kinds of medication.
conclusionThe prevalence of STIs in WLWH in Denmark was low. The need for annual STI screening is questionable. Condoms were preferred contraceptives, especially in WLWH with an HIV-negative partner. In this cohort, 13 % of WLWH of reproductive age were at risk of unintended pregnancies due to lack of birth-control. Finally, in the subgroup of WLWH receiving both hormonal contraceptives and HAART possible drug-drug interactions could occur.
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