Evidence map›Paper›PMID 26879950›Full record

ArticleThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2017

Neonatal Abstinence Syndrome in West Virginia Substate Regions, 2007-2013.

Meagan E Stabler, D Leann Long, Ilana R A Chertok, Peter R Giacobbi, Courtney Pilkerton, Laura R Lander

Open access · greenAbstract read
In one paragraph

Article in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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  6. Rural and Appalachian Disparities in Neonatal Abstinence Syndrome Incidence and Access to Opioid Abuse Treatment.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meagan E StablerDepartment of Epidemiology, School of Public Health, West Virginia University, Morgantown, West Virginia.
D Leann LongDepartment of Biostatistics, School of Public Health, West Virginia University, Morgantown, West Virginia.
Ilana R A ChertokSchool of Nursing, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, North Carolina.
Peter R GiacobbiDepartment of Sport Sciences with Joint Appointment to Department of Epidemiology, School of Public Health, West Virginia University, Morgantown, West Virginia.
Courtney PilkertonDepartment of Epidemiology, School of Public Health, West Virginia University, Morgantown, West Virginia.
Laura R LanderDepartment of Behavioral Medicine and Psychiatry, School of Medicine, West Virginia University, Morgantown, West Virginia.
West Virginia University · USUniversity of North Carolina at Charlotte · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

purposeThe opioid epidemic is a public health threat with consequences affecting newborns. Neonatal Abstinence Syndrome (NAS) is a constellation of withdrawal symptoms resulting primarily from in utero opioid exposure. The purpose of this study was to examine NAS and drug-specific trends in West Virginia (WV), where rurality-related issues are largely present.

methodsThe 2007-2013 WV Health Care Authority, Uniform Billing Data were analyzed for 119,605 newborn admissions with 1,974 NAS diagnoses. NAS (ICD9-CM 779.5) and exposure diagnostic codes for opioids, hallucinogens, and cocaine were utilized as incidence rate (IR) per 1,000 live births.

findingsBetween 2007 and 2013, NAS IR significantly increased from 7.74 to 31.56 per 1,000 live births per year (Z: -19.10, P < .0001). During this time period, opioid exposure increased (Z: -9.56, P < .0001), while cocaine exposure decreased (Z: 3.62, P = .0003). In 2013, the southeastern region of the state had the highest NAS IR of 48.76 per 1,000 live births. NAS infants were more likely to experience other clinical conditions, longer hospital stay, and be insured by Medicaid.

conclusionsStatewide NAS IR increased 4-fold over the study period, with rates over 3 times the national annual averages. This alarming trend is deleterious for the health of WV mother-child dyads and it strains the state's health care system. Therefore, WV has a unique need for prenatal public health drug treatment and prevention resources, specifically targeting the southeastern region. Further examination of maternal drug-specific trends and general underutilization of neonatal exposure ICD-9-CM codes is indicated.

Indexed as

Geographic MappingAnalgesics, OpioidChi-Square DistributionCocaineCross-Sectional StudiesHallucinogensHumansInfant, NewbornLength of StayNeonatal Abstinence SyndromeSubstance-Related DisordersWest VirginiaAnalgesics, OpioidCocaineHallucinogensgeographic variationneonatal abstinence syndromeopioid useprenatal drug abuserural health

Identifiers

PMID26879950
PMCPMC4987270
OpenAlexW2283183253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.