Evidence map›Paper›PMID 26879875›Full record

ReviewCurrent pain and headache reports2016

Post-herpetic Neuralgia: a Review.

Graham R Hadley, Julie A Gayle, Juan Ripoll, Mark R Jones, Charles E Argoff, Rachel J Kaye, Alan D Kaye

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 95 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 7 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 7 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. Pooled it
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  12. Varicella zoster virus infection.Nature reviews. Disease primers · 2026
    Review
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  17. [StagingZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
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  19. Article
  20. Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Graham R HadleyDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Room 656, 1542 Tulane Ave., New Orleans, LA, USA.
Julie A GayleDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Room 656, 1542 Tulane Ave., New Orleans, LA, USA.
Juan RipollDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Room 656, 1542 Tulane Ave., New Orleans, LA, USA.
Mark R JonesDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Room 656, 1542 Tulane Ave., New Orleans, LA, USA.
Charles E ArgoffDepartment of Neurology, Albany Medical College, Comprehensive Pain Center, Albany Medical Center, 43 New Scotland Avenue, MC 70, Albany, NY, USA.
Rachel J KayeDepartment of Biochemistry, Bowdoin College, Brunswick, ME, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Room 656, 1542 Tulane Ave., New Orleans, LA, USA. alankaye44@hotmail.com.
Louisiana State University Health Sciences Center New Orleans · USAlbany Medical Center Hospital · USBowdoin College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-herpetic neuralgia (PHN) is a chronic neuropathic pain condition that persists 3 months or more following an outbreak of shingles. Shingles, also known as acute herpes zoster, is associated with the reactivation of the dormant varicella zoster virus in an individual who has experienced chicken pox. PHN is associated with persistent and often refractory neuropathic pain. Patients may experience multiple types of pain including a constant deep, aching, or burning pain; a paroxysmal, lancinating pain; hyperalgesia (painful stimuli are more painful than expected); and allodynia (pain associated with typically non-painful stimuli). The pharmacological treatment of PHN may include a variety of medications including alpha-2 delta ligands (gabapentin and pregabalin), other anticonvulsants (carbamazepine), tricyclic antidepressants (amitriptyline, nortriptyline, doxepin), topical analgesics (5 % lidocaine patch, capsaicin) tramadol, or other opioids. The considerable side effect profiles of the commonly used oral medications often limit their practical use, and a combination of both topical and systemic agents may be required for optimal outcomes. Physicians and other treatment providers must tailor treatment based on the response of individual patients.

Indexed as

AminesAnticonvulsantsAntidepressive Agents, TricyclicCyclohexanecarboxylic AcidsEvidence-Based MedicineGabapentingamma-Aminobutyric AcidHumansNeuralgia, PostherpeticPractice Guidelines as TopicSeverity of Illness IndexTreatment OutcomeAminesAnticonvulsantsAntidepressive Agents, TricyclicCyclohexanecarboxylic AcidsGabapentingamma-Aminobutyric AcidAnalgesiaChronic painGabapentinPost-herpetic neuralgiaPregabalinTricyclic antidepressantsVaricella zoster

Identifiers

PMID26879875
OpenAlexW2280066253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.