ArticleBMC research notes2016
Prevalence of chlamydia among HIV positive and HIV negative patients in the Vhembe District as detected by real time PCR from urine samples.
Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Global mapping of sexually transmitted Chlamydia trachomatis disease: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Characterizing sexual violence perpetrated by adolescents in South Africa and associations with HIV and STI risk behaviors.Psychology of violence · 2026Article
- A conceptual framework for integrating HIV, STIs and pregnancy prevention services in Vhembe District, Limpopo, South Africa: improving teenagers' health outcomes.BMC public health · 2026Article
- Development and Validation of an Integrated HIV/STI, and Pregnancy Prevention Programme: Improving Adolescent Sexual Health Outcomes.Tropical medicine and infectious disease · 2025Article
- Prevalence and management of syphilis at primary healthcare level in the Free State, South Africa.Southern African journal of infectious diseases · 2025Article
- Evaluating the Implementation of Adolescent- and Youth-Friendly Services in the Selected Primary Healthcare Facilities in Vhembe District, Limpopo Province.International journal of environmental research and public health · 2024Article
- Seroprevalence ofLe infezioni in medicina · 2024Article
- When Bacteria and Viruses Collide: A Tale ofViruses · 2023Review
- Ensuring equity with pre-clinical planning for chlamydia vaccines.NPJ vaccines · 2023Review
- LncRNA SNHG10 suppresses the development of doxorubicin resistance by downregulating miR-302b in triple-negative breast cancer.Bioengineered · 2022Article
- Evaluation of the Predictive Value of Urine Leukocyte Esterase Test inFrontiers in medicine · 2022Article
- Incidence and risk factors of C. trachomatis and N. gonorrhoeae among young women from the Western Cape, South Africa: The EVRI study.PloS one · 2021Article
- High prevalence of Chlamydia trachomatis in pregnant women attended at Primary Health Care services in Amazon, Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- High prevalence of asymptomatic sexually transmitted infections among human immunodeficiency virus-infected pregnant women in a low-income South African community.International journal of STD & AIDS · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChlamydia is a bacterial infection that has long plagued humanity as the most commonly contracted STD and is caused by Chlamydia trachomatis. With the emergence of HIV/AIDS, sexually transmitted diseases have also re-emerged as a grave public health problem, particularly in developing countries. Updated Information about the relative frequencies in developing countries is sparse. This study aims at establishing the relative occurrence of chlamydia using real time PCR technique in the Vhembe District of South Africa where reports on the prevalence of chlamydia are not available.
methodsA total of 243 Urine samples were collected from patients attending different ARV clinics in the Vhembe District and genomic DNA was purified using blood genomic DNA kit from Sigma-Aldrich. Real-Time PCR protocol targeting the 16S rRNA gene of C. trachomatis was used to confirm the presence of chlamydia among these patients. Demographic information as well as clinical data was collected as well.
resultsOf all the participants, 70.4% were females. The age varied from 19 to 72 years. The overall prevalence of chlamydia was 32.1%. The prevalence was significantly higher among females (39.2%) compared to males (15.5%) patients (P = 0.001) and was highest among pregnant women followed by patients who had reported any allergic reaction. Among the HIV positive patients, the prevalence was higher among those who were not taking ARV (38.1%) compared to those who were taking them (28.5%). The age group within which the highest prevalence was found was between 26-45 years.
conclusionsThe present study shows a high prevalence of chlamydia among HIV and AIDS patients in the Vhembe District emphasizing the need to enhance STI control and particularly chlamydia among all young people. The particularly high prevalence of chlamydia among pregnant women is of great concern as this predisposes them to complications, while allergy migh predispose people to chlamydia infections. Further studies are needed in the general population both HIV positive and HIV negative persons to further determine the impact of these infections in the community.
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