ReviewCurrent genetics2016
Regulation of the fungal secretome.
Review in Current genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
50 citing papers in PubMed.
- Machine-Learning Prediction of Extracellular Vesicle Protein Sorting Expands the Characterization of Secretory Functions inJournal of fungi (Basel, Switzerland) · 2026Article
- Hyaluronic acid degradation by Purpureocillium lilacinum: biochemical and transcriptomic insights.Applied microbiology and biotechnology · 2026Article
- Regulation of extracellular vesicles for protein secretion inMicrobial cell (Graz, Austria) · 2026Article
- High hydrostatic pressure enhances chitinase activity and reveals metabolic regulation via transcriptomics in an abyssal fungus Purpureocillium lilacinum FDZ8Y1.Microbial cell factories · 2025Article
- Cell walls of filamentous fungi - challenges and opportunities for biotechnology.Applied microbiology and biotechnology · 2025Review
- Unveiling the molecular arsenal: genome sequencing andFrontiers in plant science · 2025Article
- Elucidating Thermothielavioides terrestris secretome changes for improved saccharification of mild steam-pretreated spruce.Biotechnology for biofuels and bioproducts · 2024Article
- Genome sequencing of Elaeocarpus spp. stem blight pathogen Pseudocryphonectria elaeocarpicola reveals potential adaptations to colonize woody bark.BMC genomics · 2024Article
- Insights into the efficient degradation mechanism of extracellular proteases mediated byFrontiers in microbiology · 2024Article
- The Promoting Mechanism of the Sterile Fermentation Filtrate ofBiomolecules · 2023Article
- Secretome Analysis for a New Strain of the Blackleg FungusJournal of fungi (Basel, Switzerland) · 2023Article
- The Lost and Found: Unraveling the Functions of Orphan Genes.Journal of developmental biology · 2023Review
- Comparative analysis of simulatedFrontiers in microbiology · 2023Article
- Draft genome sequencing ofFrontiers in microbiology · 2023Article
- Identification and analysis of the secretome of plant pathogenic fungi reveals lifestyle adaptation.Frontiers in microbiology · 2023Article
- Verticillium dahliae Vta3 promotes ELV1 virulence factor gene expression in xylem sap, but tames Mtf1-mediated late stages of fungus-plant interactions and microsclerotia formation.PLoS pathogens · 2023Article
- Pectinases Secretion byMolecules (Basel, Switzerland) · 2022Article
- Leveraging genomics to understand the broader role of fungal small secreted proteins in niche colonization and nutrition.ISME communications · 2022Review
- The development of extracellular vesicle markers for the fungal phytopathogen Colletotrichum higginsianum.Journal of extracellular vesicles · 2022Article
- Impairment of the cellulose degradation machinery enhancesScience advances · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of countless representatives of the Kingdom Fungi to adapt to and proliferate in diverse environments is facilitated by regulation of their secretomes to respond to changes in environmental conditions and to mediate interactions with other organisms. Secretome changes often fulfill common functions of nutrient acquisition, facilitation of host/symbiont interactions, cell wall modification, and optimization of the enzyme suite to adapt to new environmental resources. In this review, we expand on our recent work on signaling and the secretome in the pathogenic fungus Cryptococcus neoformans to consider a range of selected examples of regulation of fungal secretomes. These examples include the impact of carbon source and aspects of the response to plant and animal hosts. Additionally, the influence of key protein kinases (e.g., Pka1, Snf1) and transcription factors (e.g., Rim101/PacC) is highlighted to illustrate some underlying regulatory factors influencing the secretome. Although there is a wealth of information about fungal secretomes from both experimentation and genome sequence mining, there are also major gaps in our knowledge about the complete composition of fungal secretomes and mechanisms of dynamic change. For example, a more comprehensive understanding of the composition and regulation of the secretome will require consideration of the emerging roles of unconventional secretion and extracellular vesicles in delivering proteins outside the cell. Overall, changes in the secretome are well documented in diverse fungi and the underlying mechanisms are currently under investigation; however, there remain unknown steps in the regulation of secretory pathways and gaps in understanding the regulation of unconventional secretion, which warrant further research.
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