Evidence map›Paper›PMID 26879079›Full record

ReviewCurrent atherosclerosis reports2016

An Update on the Utility of Coronary Artery Calcium Scoring for Coronary Heart Disease and Cardiovascular Disease Risk Prediction.

Sina Kianoush, Mahmoud Al Rifai, Miguel Cainzos-Achirica, Priya Umapathi, Garth Graham, Roger S Blumenthal, Khurram Nasir, Michael J Blaha

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Pregnancy history, coronary artery calcification and bone mineral density in menopausal women.Climacteric : the journal of the International Menopause Society · 2018
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sina KianoushJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA.
Mahmoud Al RifaiJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA.
Miguel Cainzos-AchiricaJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA.
Priya UmapathiJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA.
Garth GrahamAetna Foundation, Hartford, CT, USA.
Roger S BlumenthalJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA.
Khurram NasirJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA.
Michael J BlahaJohns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, 21287, USA. mblaha1@jhmi.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimating cardiovascular disease (CVD) risk is necessary for determining the potential net benefit of primary prevention pharmacotherapy. Risk estimation relying exclusively on traditional CVD risk factors may misclassify risk, resulting in both undertreatment and overtreatment. Coronary artery calcium (CAC) scoring personalizes risk prediction through direct visualization of calcified coronary atherosclerotic plaques and provides improved accuracy for coronary heart disease (CHD) or CVD risk estimation. In this review, we discuss the most recent studies on CAC, which unlike historical studies, focus sharply on clinical application. We describe the MESA CHD risk calculator, a recently developed CAC-based 10-year CHD risk estimator, which can help guide preventive therapy allocation by better identifying both high- and low-risk individuals. In closing, we discuss calcium density, regional distribution of CAC, and extra-coronary calcification, which represent the future of CAC and CVD risk assessment research and may lead to further improvements in risk prediction.

Indexed as

CalcinosisCalciumCardiovascular DiseasesCoronary Artery DiseaseHumansPrimary PreventionRisk FactorsCalciumCardiovascular diseaseCoronary artery calciumCoronary heart diseasePrimary preventionRisk assessmentStatins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.