Evidence map›Paper›PMID 26878279›Full record

ArticleThe Analyst2016

Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis.

Jie Ding, Robert M Lawrence, Paul V Jones, Brenda G Hogue, Mark A Hayes

Abstract read
In one paragraph

Article in The Analyst, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  12. Micro and Nanoscale Technologies for Diagnosis of Viral Infections.Small (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie DingSchool of Molecular Sciences, Arizona State University, Tempe, Arizona, USA. mhayes@asu.edu.
Robert M LawrenceThe Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona, USA and Center for Applied Structural Design, The Biodesign Institute, Arizona State University, Tempe, Arizona, USA.
Paul V JonesSchool of Molecular Sciences, Arizona State University, Tempe, Arizona, USA. mhayes@asu.edu.
Brenda G HogueSchool of Life Sciences, Arizona State University, Tempe, Arizona, USA and The Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona, USA and Center for Applied Structural Design, The Biodesign Institute, Arizona State University, Tempe, Arizona, USA.
Mark A HayesSchool of Molecular Sciences, Arizona State University, Tempe, Arizona, USA. mhayes@asu.edu.

Funding

Isolating Viral Particles from Whole BloodR03AI094193 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HAYES, MARK A, HOGUE, BRENDA G. · 2012 to 2013
$138k
Pathogen Isolation and Concentration for Phenotypic SubtypingR03AI099740 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HAYES, MARK A · 2012 to 2013
$138k
Isolation of Pathogenic ListeriaR03AI111361 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HAYES, MARK A · 2015 to 2016
$136k
NIAID NIH HHS 1R03AI094193-01NIAID NIH HHS 1R03AI099740-01NIAID NIH HHS R03 AI094193NIAID NIH HHS R03 AI099740NIAID NIH HHS R03 AI111361NIAID NIH HHS R03AI111361-01
6 · The paper itself

Abstract

Biotechnology, separation science, and clinical research are impacted by microfluidic devices. Separation and manipulation of bioparticles such as DNA, protein and viruses are performed on these platforms. Microfluidic systems provide many attractive features, including small sample size, rapid detection, high sensitivity and short processing time. Dielectrophoresis (DEP) and electrophoresis are especially well suited to microscale bioparticle control and have been demonstrated in many formats. In this work, an optimized gradient insulator-based DEP device was utilized for concentration of Sindbis virus, an animal virus with a diameter of 68 nm. Within only a few seconds, the concentration of Sindbis virus can be increased by two to six times in the channel under easily accessible voltages as low as about 70 V. Compared with traditional diagnostic methods used in virology, DEP-based microfluidics can enable faster isolation, detection and concentration of viruses in a single step within a short time.

Indexed as

ElectrophoresisFinite Element AnalysisLab-On-A-Chip DevicesSindbis Virus

Identifiers

PMID26878279
PMCPMC6426443

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.