Evidence map›Paper›PMID 26877623›Full record

ArticleEthics & behavior2015

Stakeholder Opinions And Ethical Perspectives Support Complete Disclosure Of Incidental Findings In MRI Research.

John P Phillips, Caitlin Cole, John P Gluck, Jody M Shoemaker, Linda Petree, Deborah Helitzer, Ronald Schrader, Mark Holdsworth

Abstract read
In one paragraph

Article in Ethics & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. A Just Standard: The Ethical Management of Incidental Findings in Brain Imaging Research.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2021
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John P PhillipsDepartment of Neurology, University of New Mexico & The Mind Research Network, Albuquerque, New Mexico 87106.
Caitlin ColeThe Mind Research Network, Albuquerque, New Mexico 87106, ccole@mrn.org.
John P GluckKennedy Institute of Ethics, Georgetown University, Washington, DC 20057, jgluck@unm.edu.
Jody M ShoemakerThe Mind Research Network, Albuquerque, New Mexico 87106, jroberts@mrn.org.
Linda PetreeThe Mind Research Network, lpetree@mrn.org.
Deborah HelitzerDepartment of Family Practice, University of New Mexico Health Science Center, helitzer@salud.unm.edu.
Ronald SchraderClinical and Translational Science Center, University of New Mexico Health Science Center, RSchrader@salud.unm.edu.
Mark HoldsworthCollege of Pharmacy, University of New Mexico Health Science Center, MHoldsworth@salud.unm.edu.

Funding

University of New Mexico Clinical and Translational Science CenterUL1TR000041 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LARSON, RICHARD S · 2012 to 2014
$9.8M
Optimization of incidental findings disclosure to research subjectsR21NS077050 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI HOLDSWORTH, MARK T, PHILLIPS, JOHN P · 2012 to 2013
$443k
NCATS NIH HHS UL1 TR000041NINDS NIH HHS R21 NS077050
6 · The paper itself

Abstract

How far does a researcher's responsibility extend when an incidental finding is identified? Balancing pertinent ethical principles such as beneficence, respect for persons, and duty to rescue is not always straightforward, particularly in neuroimaging research where empirical data that might help guide decision-making is lacking. We conducted a systematic survey of perceptions and preferences of 396 investigators, research participants and IRB members at our institution. Using the partial entrustment model as described by Richardson, we argue that our data supports universal reading by a neuroradiologist of all research MRI scans for incidental findings and providing full disclosure to all participants.

Indexed as

imagingincidental findingspaternalismresearch ethics

Identifiers

PMID26877623
PMCPMC4749272

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.