Evidence map›Paper›PMID 26877599›Full record

ArticleZhongguo sheng wu hua xue yu fen zi sheng wu xue bao = Chinese journal of biochemistry and molecular biology

Mechanism and Function of Angiogenin in Hematopoietic Malignancy.

Kevin A Goncalves, Guo-Fu Hu

Open access · greenAbstract read
In one paragraph

Article in Zhongguo sheng wu hua xue yu fen zi sheng wu xue bao = Chinese journal of biochemistry and molecular biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kevin A GoncalvesMolecular Oncology Research Institute, Tufts Medical Center.
Guo-Fu HuMolecular Oncology Research Institute, Tufts Medical Center.
Molecular Oncology (United States) · US

Funding

The mechanism of angiogenin-induced angiogenesisR01CA105241 · NCI · TUFTS MEDICAL CENTER · PI HU, GUO-FU · 2005 to 2015
$2.8M
Angiogenin in ALS Pathobiology and TherapyR01NS065237 · NINDS · TUFTS MEDICAL CENTER · PI HU, GUO-FU · 2010 to 2014
$1.8M
Role of Angiogenin in Hematopoietic Stem Cell Quiescence and Self-renewalF31HL128127 · NHLBI · TUFTS UNIVERSITY BOSTON · PI GONCALVES, KEVIN A · 2015 to 2016
$43k
NCI NIH HHS R01 CA105241NHLBI NIH HHS F31 HL128127NINDS NIH HHS R01 NS065237
6 · The paper itself

Abstract

Angiogenic factors have been widely implicated in the formation and progression of solid tumors. A number of angiogenic mediators have been recently appreciated as having equivalent function in non-solid tumors, such as leukemia. One such factor, angiogenin (ANG), promotes tumor cell growth and angiogenesis in solid cancers; however its precise function(s) in hematological disorders are not fully understood. This review summarizes current knowledge of the function and therapeutic potential of angiogenic factors, with particular emphasis on the role and hypothesized mechanism of ANG in a non-solid tumor setting.

Indexed as

angiogenesisangiogeninbone marrow diseasescancercell proliferationleukemiamalignant hematopoiesisRNA processing

Identifiers

PMID26877599
PMCPMC4750500
OpenAlexW2412703630

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.