Evidence map›Paper›PMID 26877260›Full record

SynthesisScientific reports2016

Dairy Product, Calcium Intake and Lung Cancer Risk: A Systematic Review with Meta-Analysis.

Yang Yang, Xu Wang, Qinghua Yao, Liqiang Qin, Chao Xu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 6 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  14. Food, Nutrition, Physical Activity and Microbiota: Which Impact on Lung Cancer?International journal of environmental research and public health · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yang YangDepartment of Radiation Therapy, Zhejiang Cancer Hospital, Hangzhou, China.
Xu WangDepartment of Radiology, Zhejiang Cancer Hospital, Hangzhou, China.
Qinghua YaoDepartment of Integrated Traditional Chinese and Western Medicine, Zhejiang Cancer Hospital; Key Laboratory of Integrated Traditional Chinese and Western Medicine Hangzhou, Hangzhou, China.
Liqiang QinDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Chao XuDepartment of Integrated Traditional Chinese and Western Medicine, Zhejiang Cancer Hospital; Key Laboratory of Integrated Traditional Chinese and Western Medicine Hangzhou, Hangzhou, China.
Zhejiang Cancer Hospital · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of dairy products on human health have been studied for years. However, the relationship between dairy products as well as calcium intake and the risk of lung cancer is still inconclusive. A total of 32 studies regarding this association were identified from the PubMed and Web of Science databases through April 1, 2015, including 12 cohort studies and 20 case-control studies. After pooling the results of individual studies, the summary RRs (relative risks) of lung cancer for the highest versus lowest intake were 1.05 (95%CI: 0.84-1.31) and 1.08 (95%CI: 0.80-1.46) for total dairy products and milk, respectively. The results on the consumption of cheese, yogurt and low-fat milk were also negative, and the RRs for total and dietary calcium intakes were 0.99 (95%CI: 0.70-1.38) and 0.85 (95%CI: 0.63-1.13), respectively. After stratifying by potential confounders, the results remained consistent in most subgroup analyses. Our study indicates that intake of dairy products or calcium was not statistically associated with the risk of lung cancer. This negative finding provides a conclusive answer to the disease association issue based on current evidence, and suggests that further efforts should be made to find other nutritional risk factors for lung cancer.

Indexed as

Calcium, DietaryCase-Control StudiesDairy ProductsDietFemaleHumansLung NeoplasmsMaleRisk AssessmentCalcium, Dietary

Identifiers

PMID26877260
PMCPMC4753428
OpenAlexW2275899828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.