Evidence map›Paper›PMID 26877132›Full record

ArticlePsychophysiology2016

Psychoneurometric operationalization of threat sensitivity: Relations with clinical symptom and physiological response criteria.

James R Yancey, Noah C Venables, Christopher J Patrick

Abstract readTwin Study
In one paragraph

Article in Psychophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
  2. Article
  3. Opposing Relations of Reward Positivity with Anhedonia and Threat Sensitivity: Implications for Differential Dimensional Diagnosis.Clinical psychological science : a journal of the Association for Psychological Science · 2025
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  11. Trait boldness and emotion regulation: An event-related potential investigation.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022
    Article
  12. A Hierarchical Taxonomy of Psychopathology (HiTOP) Primer for Mental Health Researchers.Clinical psychological science : a journal of the Association for Psychological Science · 2022
    Article
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  17. Review
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  19. Using a co-twin control design to evaluate alternative trait measures as indices of liability for substance use disorders.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James R YanceyFlorida State University.
Noah C VenablesFlorida State University.
Christopher J PatrickFlorida State University.
Florida State University · US

Funding

Project 6: Individual Differences in the Motivational Substrates (pg 275)P50MH072850 · NIMH · UNIVERSITY OF FLORIDA · PI LANG, PETER J · 2005 to 2009
$8.8M
Trait Fear and Disinhibition in Impulse Control DisordersRC1MH089727 · NIMH · FLORIDA STATE UNIVERSITY · PI PATRICK, CHRISTOPHER JOHN · 2009 to 2010
$942k
NIMH NIH HHS MH072850NIMH NIH HHS MH089727NIMH NIH HHS P50 MH072850NIMH NIH HHS RC1 MH089727
6 · The paper itself

Abstract

The National Institute of Mental Health's Research Domain Criteria (RDoC) initiative calls for the incorporation of neurobiological approaches and findings into conceptions of mental health problems through a focus on biobehavioral constructs investigated across multiple domains of measurement (units of analysis). Although the constructs in the RDoC system are characterized in "process terms" (i.e., as functional concepts with brain and behavioral referents), these constructs can also be framed as dispositions (i.e., as dimensions of variation in biobehavioral functioning across individuals). Focusing on one key RDoC construct, acute threat or "fear," the current article illustrates a construct-oriented psychoneurometric strategy for operationalizing this construct in individual difference terms-as threat sensitivity (THT+). Utilizing data from 454 adult participants, we demonstrate empirically that (a) a scale measure of THT+ designed to tap general fear/fearlessness predicts effectively to relevant clinical problems (i.e., fear disorder symptoms), (b) this scale measure shows reliable associations with physiological indices of acute reactivity to aversive visual stimuli, and (c) a cross-domain factor reflecting the intersection of scale and physiological indicators of THT+ predicts effectively to both clinical and neurophysiological criterion measures. Results illustrate how the psychoneurometric approach can be used to create a dimensional index of a biobehavioral trait construct, in this case THT+, which can serve as a bridge between phenomena in domains of psychopathology and neurobiology. Implications and future directions are discussed with reference to the RDoC initiative and existing report-based conceptions of psychological traits.

Indexed as

Neuropsychological TestsAdultCerebral CortexElectromyographyFaceFearFemaleHeart RateHumansMaleNational Institute of Mental Health (U.S.)Phobic DisordersReflex, StartleUnited StatesIndividual differencesOtherPsychopathology

Identifiers

PMID26877132
PMCPMC4756387
OpenAlexW2341877857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.