ReviewCurrent topics in medicinal chemistry2016
The Unexpected Advantages of Using D-Amino Acids for Peptide Self- Assembly into Nanostructured Hydrogels for Medicine.
Review in Current topics in medicinal chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed.
- Enzyme-Instructed Self-Assembling Peptide Hydrogels for Sustained Subconjunctival Delivery of Dexamethasone: A Stereochemical Comparison of L- and D-Enantiomeric Peptides for Postoperative Ocular Anti-Inflammatory Therapy.Gels (Basel, Switzerland) · 2026Article
- Tyrosine-capped gold nanoparticles enable cysteine-free peptide loading, enhancing the antipseudomonal efficacy of scorpion-derived AamAP1-Lys-NHJournal of materials chemistry. B · 2026Article
- Phase separation of a heterochiral peptide-drug conjugate amplified by ionic interactions.Nature communications · 2026Article
- Chirality Effect on Physical and Biological Properties of Peptide-Based Hydrogels.Gels (Basel, Switzerland) · 2026Review
- Stability and biocompatibility of hBD3 with different chiral configurations and their therapeutic efficacy in periodontitis.iScience · 2025Article
- Minimalistic Peptide Nanocarriers for Multiple Cancer Drugs.ACS applied bio materials · 2025Article
- Modulating Peptide Self-Assembly via Triblock Chiral Patterning.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- AMP-IBP5: A Multifunctional Antimicrobial Peptide for Advanced Wound Healing and Inflammatory Skin Disorders.Journal of functional biomaterials · 2025Review
- Article
- A Snake Venom Peptide and Its Derivatives Prevent AβACS chemical neuroscience · 2024Article
- Biostable hydrogels consisting of hybrid β-sheet fibrils assembled by a pair of enantiomeric peptides.Materials today. Bio · 2024Article
- Tuning tRNAs for improved translation.Frontiers in genetics · 2024Review
- Short Peptides for Hydrolase Supramolecular Mimicry and Their Potential Applications.Gels (Basel, Switzerland) · 2023Review
- Self-Assembled Peptide Hydrogels in Regenerative Medicine.Gels (Basel, Switzerland) · 2023Review
- Mirror Image Mucins and Thio Mucins with Tunable Biodegradation.Journal of the American Chemical Society · 2023Article
- Enzyme-Triggered l-α/d-Peptide Hydrogels as a Long-Acting Injectable Platform for Systemic Delivery of HIV/AIDS Drugs.Advanced healthcare materials · 2023Article
- Self-Assembled Peptide Nanostructures for ECM Biomimicry.Nanomaterials (Basel, Switzerland) · 2022Review
- Minimalist De Novo Design of an Artificial Enzyme.ACS omega · 2022Article
- A short peptide derived from pigment epithelial-derived factor exhibits an angioinhibitory effect.BMC ophthalmology · 2022Article
- Polymer Conjugates of Antimicrobial Peptides (AMPs) with d-Amino Acids (d-aa): State of the Art and Future Opportunities.Pharmaceutics · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Self-assembled peptide hydrogels have brought innovation to the medicinal field, not only as responsive biomaterials but also as nanostructured therapeutic agents or as smart drug delivery systems. D-amino acids are typically introduced to increase the peptide enzymatic stability. However, there are several reports of unexpected effects on peptide conformation, self-assembly behavior, cytotoxicity and even therapeutic activity. This mini-review discusses all the surprising twists of heterochiral self-assembled peptide hydrogels, and delineates emerging key findings to exploit all the benefits of D-amino acids in this novel medicinal area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.