Evidence map›Paper›PMID 26876234›Full record

ArticleDental materials : official publication of the Academy of Dental Materials2016

Near-infrared imaging of secondary caries lesions around composite restorations at wavelengths from 1300-1700-nm.

Jacob C Simon, Seth A Lucas, Robert C Lee, Cynthia L Darling, Michal Staninec, Ram Vaderhobli, Roger Pelzner, Daniel Fried

Open access · greenAbstract read
In one paragraph

Article in Dental materials : official publication of the Academy of Dental Materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Atlas of Dental Near-Infrared Transillumination Images.Diagnostics (Basel, Switzerland) · 2024
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  17. High-Contrast Reflectance Imaging of Composite Restorations Color-Matched to Tooth Structure at 1000-2300-nm.Proceedings of SPIE--the International Society for Optical Engineering · 2017
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jacob C SimonDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Seth A LucasDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Robert C LeeDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Cynthia L DarlingDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Michal StaninecDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Ram VaderhobliDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Roger PelznerDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States.
Daniel FriedDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, United States. Electronic address: daniel.fried@ucsf.edu.
University of California, San Francisco · US

Funding

UCSF INTEGRATED DDS-PHD TRAINING PROGRAMT32DE007306 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Yukiko Nakano · 1996 to 2026
$15.4M
Early Caries Detection with Near-IR LightR01DE014698 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2002 to 2016
$4.0M
Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCTR01DE017869 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2006 to 2014
$2.6M
NIDCR NIH HHS R01 DE014698NIDCR NIH HHS R01 DE017869NIDCR NIH HHS R01-DE14698NIDCR NIH HHS R01DE17869NIDCR NIH HHS T32 DE007306
6 · The paper itself

Abstract

BACKGROUND AND

objectivesCurrent clinical methods for diagnosing secondary caries are unreliable for identifying the early stages of decay around restorative materials. The objective of this study was to access the integrity of restoration margins in natural teeth using near-infrared (NIR) reflectance and transillumination images at wavelengths between 1300 and 1700-nm and to determine the optimal NIR wavelengths for discriminating composite materials from dental hard tissues. MATERIALS AND

methodsTwelve composite margins (n=12) consisting of class I, II and V restorations were chosen from ten extracted teeth. The samples were imaged in vitro using NIR transillumination and reflectance, polarization sensitive optical coherence tomography (PS-OCT) and a high-magnification digital microscope. Samples were serially sectioned into 200-μm slices for histological analysis using polarized light microscopy (PLM) and transverse microradiography (TMR). Two independent examiners evaluated the presence of demineralization at the sample margin using visible detection with 10× magnification and NIR images presented digitally. Composite restorations were placed in sixteen sound teeth (n=16) and imaged at multiple NIR wavelengths ranging from λ=1300 to 1700-nm using NIR transillumination. The image contrast was calculated between the composite and sound tooth structure.

resultsIntensity changes in NIR images at wavelengths ranging from 1300 to 1700-nm correlate with increased mineral loss measured using TMR. NIR reflectance and transillumination at wavelengths coincident with increased water absorption yielded significantly higher (P<0.001) contrast between sound enamel and adjacent demineralized enamel. In addition, NIR reflectance exhibited significantly higher (P<0.01) contrast between sound enamel and adjacent composite restorations than visible reflectance. SIGNIFICANCE: This study shows that NIR imaging is well suited for the rapid screening of secondary caries lesions.

Indexed as

Dental Restoration, PermanentComposite ResinsDental CariesHumansIn Vitro TechniquesLasers, GasMicroradiographyMicroscopy, PolarizationSpectroscopy, Near-InfraredTomography, Optical CoherenceTooth DemineralizationTransilluminationComposite ResinsComposite restorative materialsNear-IR imagingOptical coherence tomographySecondary caries

Identifiers

PMID26876234
PMCPMC4801720
OpenAlexW2256587082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.