Evidence map›Paper›PMID 26876035›Full record

ReviewNature reviews. Microbiology2016

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution.

Alan McNally, Nicholas R Thomson, Sandra Reuter, Brendan W Wren

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 152 citations in OpenAlex.

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  11. Multiplex PCR System for the Diagnosis of Plague.Current molecular medicine · 2025
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  12. Design of a novel multi-epitope vaccine candidate againstBiochemistry and biophysics reports · 2024
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  16. Review
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  19. Overview ofBiology · 2023
    Review
  20. A frameshift ineLife · 2023
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Alan McNallyPathogen Research Group, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK.
Nicholas R ThomsonPathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
Sandra ReuterDepartment of Medicine, University of Cambridge, Box 157 Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK.
Brendan W WrenDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Addenbrooke's Hospital · GBLondon School of Hygiene & Tropical Medicine · GBNottingham Trent University · GBWellcome Sanger Institute · GB

Funding

Biotechnology and Biological Sciences Research CouncilWellcome Trust 098051
6 · The paper itself

Abstract

Pathogenic species in the Yersinia genus have historically been targets for research aimed at understanding how bacteria evolve into mammalian pathogens. The advent of large-scale population genomic studies has greatly accelerated the progress in this field, and Yersinia pestis, Yersinia pseudotuberculosis and Yersinia enterocolitica have once again acted as model organisms to help shape our understanding of the evolutionary processes involved in pathogenesis. In this Review, we highlight the gene gain, gene loss and genome rearrangement events that have been identified by genomic studies in pathogenic Yersinia species, and we discuss how these findings are changing our understanding of pathogen evolution. Finally, as these traits are also found in the genomes of other species in the Enterobacteriaceae, we suggest that they provide a blueprint for the evolution of enteropathogenic bacteria.

Indexed as

Evolution, MolecularGenome, BacterialRegulonAnimalsEnterobacteriaceaeHumansInsect VectorsModels, MolecularMultigene FamilyPhylogenyYersiniaYersinia enterocoliticaYersinia InfectionsYersinia pestisYersinia pseudotuberculosis

Identifiers

PMID26876035
OpenAlexW2277680101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.