Evidence map›Paper›PMID 26875980›Full record

ReviewInternational journal of molecular sciences2016

Endocannabinoids as Guardians of Metastasis.

Irmgard Tegeder

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells.Toxicology in vitro : an international journal published in association with BIBRA · 2022
    Article
  8. Receptor-Dependent and Independent Regulation of Voltage-Gated CaInternational journal of molecular sciences · 2021
    Review
  9. The Immune Endocannabinoid System of the Tumor Microenvironment.International journal of molecular sciences · 2020
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Irmgard TegederInstitute of Clinical Pharmacology, University Hospital Frankfurt, Germany. tegeder@em.uni-frankfurt.de.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocannabinoids including anandamide and 2-arachidonoylglycerol are involved in cancer pathophysiology in several ways, including tumor growth and progression, peritumoral inflammation, nausea and cancer pain. Recently we showed that the endocannabinoid profiles are deranged during cancer to an extent that this manifests in alterations of plasma endocannabinoids in cancer patients, which was mimicked by similar changes in rodent models of local and metastatic cancer. The present topical review summarizes the complexity of endocannabinoid signaling in the context of tumor growth and metastasis.

Indexed as

AnimalsAntineoplastic AgentsArachidonic AcidsCannabinoidsEndocannabinoidsEthanolamineGlyceridesHumansNeoplasm MetastasisNeoplasmsOleic AcidsReceptors, CannabinoidTumor MicroenvironmentAntineoplastic AgentsArachidonic AcidsCannabinoidsEndocannabinoidsEthanolamineGlyceridesglyceryl 2-arachidonateOleic AcidsOleylethanolamideReceptors, Cannabinoid2-arachidonoylglycerolanandamideangiogenesisendocannabinoidsimmune cellsorphan G-protein coupled receptor

Identifiers

PMID26875980
PMCPMC4783962
OpenAlexW2255714058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.