ArticleScientific reports2016
Evidence from Multiple Species that Spider Silk Glue Component ASG2 is a Spidroin.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 62 citations in OpenAlex.
- Post-translational modifications of silk proteins.RSC chemical biology · 2026Review
- From fibres to adhesives: evolution of spider capture threads from web anchors by radical changes in silk gland function.Journal of the Royal Society, Interface · 2024Article
- Special Prey, Special Glue: NMR Spectroscopy on Aggregate Glue Components of Moth-Specialist Spiders, Cyrtarachninae.Biomimetics (Basel, Switzerland) · 2024Article
- Protein-Based Biological Materials: Molecular Design and Artificial Production.Chemical reviews · 2023Review
- The evolutionary history of cribellate orb-weaver capture thread spidroins.BMC ecology and evolution · 2022Article
- Bio-based and bio-inspired adhesives from animals and plants for biomedical applications.Materials today. Bio · 2022Review
- Solution Structure of Tubuliform Spidroin N-Terminal Domain and Implications for pH Dependent Dimerization.Frontiers in molecular biosciences · 2022Article
- Recombinant Spider Silk: Promises and Bottlenecks.Frontiers in bioengineering and biotechnology · 2022Review
- High mechanical property silk produced by transgenic silkworms expressing the spidroins PySp1 and ASG1.Scientific reports · 2021Article
- Protein Composition and Associated Material Properties of Cobweb Spiders' Gumfoot Glue Droplets.Integrative and comparative biology · 2021Article
- Shifts in morphology, gene expression, and selection underlie web loss in Hawaiian Tetragnatha spiders.BMC ecology and evolution · 2021Article
- Spidroin profiling of cribellate spiders provides insight into the evolution of spider prey capture strategies.Scientific reports · 2020Article
- Properties of orb weaving spider glycoprotein glue change during Argiope trifasciata web construction.Scientific reports · 2019Article
- Toward Spider Glue: Long Read Scaffolding for Extreme Length and Repetitious Silk Family Genes AgSp1 and AgSp2 with Insights into Functional Adaptation.G3 (Bethesda, Md.) · 2019Article
- Orb weaver glycoprotein is a smart biological material, capable of repeated adhesion cycles.Die Naturwissenschaften · 2019Article
- Conservation of a pH-sensitive structure in the C-terminal region of spider silk extends across the entire silk gene family.Heredity · 2018Article
- Hygroscopic compounds in spider aggregate glue remove interfacial water to maintain adhesion in humid conditions.Nature communications · 2018Article
- Silk genes and silk gene expression in the spider Tengella perfuga (Zoropsidae), including a potential cribellar spidroin (CrSp).PloS one · 2018Article
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Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spiders in the superfamily Araneoidea produce viscous glue from aggregate silk glands. Aggregate glue coats prey-capture threads and hampers the escape of prey from webs, thereby increasing the foraging success of spiders. cDNAs for Aggregate Spider Glue 1 (ASG1) and 2 (ASG2) have been previously described from the golden orb-weaver, Nephila clavipes, and Western black widow, Latrodectus hesperus. To further investigate aggregate glues, we assembled ASG1 and ASG2 from genomic target capture libraries constructed from three species of cob-web weavers and three species of orb-web weavers, all araneoids. We show that ASG1 is unlikely to be a glue, but rather is part of a widespread arthropod gene family, the peritrophic matrix proteins. For ASG2, we demonstrate its remarkable architectural and sequence similarities to spider silk fibroins, indicating that ASG2 is a member of the spidroin gene family. Thus, spidroins have diversified into glues in addition to task-specific, high performance fibers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.