Evidence map›Paper›PMID 26875506›Full record

ReviewFamily process2017

Integrity of Literature on Expressed Emotion and Relapse in Patients with Schizophrenia Verified by a p-Curve Analysis.

Marc J Weintraub, Daniel L Hall, Julia Y Carbonella, Amy Weisman de Mamani, Jill M Hooley

Abstract readReview
In one paragraph

Review in Family process, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  3. Caregiving profiles in first episode psychosis.Social psychiatry and psychiatric epidemiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marc J WeintraubDepartment of Psychology, University of Miami, Coral Gables, FL.
Daniel L HallDepartment of Psychology, University of Miami, Coral Gables, FL.
Julia Y CarbonellaDepartment of Psychology, University of Miami, Coral Gables, FL.
Amy Weisman de MamaniDepartment of Psychology, University of Miami, Coral Gables, FL.
Jill M HooleyDepartment of Psychology, Harvard University, Cambridge, MA.

Funding

Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
NCCIH NIH HHS T32 AT000051
6 · The paper itself

Abstract

There is growing concern that much published research may have questionable validity due to phenomena such as publication bias and p-hacking. Within the psychiatric literature, the construct of expressed emotion (EE) is widely assumed to be a reliable predictor of relapse across a range of mental illnesses. EE is an index of the family climate, measuring how critical, hostile, and overinvolved a family member is toward a mentally ill patient. No study to date has examined the evidential value of this body of research as a whole. That is to say, although many studies have shown a link between EE and symptom relapse, the integrity of the literature from which this claim is derived has not been tested. In an effort to confirm the integrity of the literature of EE predicting psychiatric relapse in patients with schizophrenia, we conducted a p-curve analysis on all known studies examining EE (using the Camberwell Family Interview) to predict psychiatric relapse over a 9- to 12-month follow-up period. Results suggest that the body of literature on EE is unbiased and has integrity, as there was a significant right skew of p-values, a nonsignificant left skew of p-values, and a nonsignificant test of flatness. We conclude that EE is a robust and valuable predictor of symptom relapse in schizophrenia.

Indexed as

Expressed EmotionSchizophrenic PsychologyBiasHumansRecurrenceSchizophreniaSymptom Assessmentanálisis de la curva de uso selectivo de datosemoción expresadaesquizofreniaExpressed Emotionp-Curve AnalysisPsychiatric Relapsep曲线分析recaída psiquiátricaSchizophrenia精神分裂精神病反复表达情感

Identifiers

PMID26875506
PMCPMC5765756

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.