Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia pseudomallei Pneumonia in Paediatric Patients.

Pasco Hearn, Claudia Turner, Kuong Suy, Sona Soeng, Nicholas P J Day, Paul Turner

Open access · hybridAbstract read

In one paragraph

Article in Journal of tropical pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 99% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Pasco HearnCambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia pascohearn@hotmail.com.

Claudia TurnerCambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Angkor Hospital for Children, Siem Reap, Cambodia.

Kuong SuyCambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia.

Sona SoengCambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Angkor Hospital for Children, Siem Reap, Cambodia.

Nicholas P J DayNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Paul TurnerCambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

Cambodia-Oxford Medical Research Unit · KHUniversity of Oxford · GBAngkor Hospital for Children · KHMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of Burkholderia pseudomallei pneumonia in children is challenging. We investigated the utility of nasopharyngeal swabs taken from 194 paediatric patients on admission with radiologically proven pneumonia. Melioidosis was proven in 0.5% of samples tested and only in a third of those known to be bacteraemic with B. pseudomallei. It appears unlikely that culture of nasopharyngeal secretions is helpful to confirm B. pseudomallei pneumonia in paediatric patients.

Indexed as

Anti-Bacterial AgentsBacteremiaBurkholderia pseudomalleiCambodiaHumansMelioidosisPneumonia, BacterialRadiography, ThoracicAnti-Bacterial AgentsBurkholderia pseudomalleimelioidosisnasopharyngeal swabpaediatric

Identifiers

PMID26874977

DOI10.1093/tropej/fmv109

PMCPMC4998522

OpenAlexW2284763519

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.